YorkieTalk.com Forums - Yorkshire Terrier Community


Welcome to the YorkieTalk.com Forums Community - the community for Yorkshire Terriers.

You are currently viewing our boards as a guest which gives you limited access to view most discussions and access our other features. By joining our free community you will have access to post topics, communicate privately with other members (PM), respond to polls, upload content and access many other special features. You will be able to chat with over 35,000 YorkieTalk members, read over 2,000,000 posted discussions, and view more than 15,000 Yorkie photos in the YorkieTalk Photo Gallery after you register. We would love to have you as a member!

Registration is fast, simple and absolutely free so please, join our community today!

If you have any problems with the registration process or your account login, please click here to contact us.

Go Back   YorkieTalk.com Forums - Yorkshire Terrier Community > YorkieTalk > Sick & Injured / Emergencies Talk
Register Blogs FAQ Calendar JavaChat Mark Forums Read

Reply
 
LinkBack Thread Tools
Old 04-04-2019, 01:43 PM   #1
Senior Yorkie Talker
 
Join Date: Feb 2014
Location: Los Angeles
Posts: 114
Default CBD oil for dogs

Does anyone have experience with giving CBD oil to their dogs. Is it safe?
woofwoofwoof is offline   Reply With Quote
Welcome Guest!
Not Registered?

Join today and remove this ad!

Old 04-04-2019, 01:47 PM   #2
Yorkie mom of 4
Donating YT Member
 
Lovetodream88's Avatar
 
Join Date: Feb 2008
Location: LaPlata, Md
Posts: 22,792
Default

Its safe when used correctly and made sure there is no THC in it. I use it on my oldest and it has been amazing. I prefer human grade to the dog products and it can be expensive but generally with CBD oil the more expensive the better grade it is. What are you wanting to use it for?
__________________
Taylor
My babies Joey, Penny ,Ollie & Dixie
Callie Mae, you will forever be in my heart!
Lovetodream88 is offline   Reply With Quote
Old 04-04-2019, 01:54 PM   #3
Senior Yorkie Talker
 
Join Date: Feb 2014
Location: Los Angeles
Posts: 114
Default

I want to use it to see if maybe it shrinks the lump on my pup
woofwoofwoof is offline   Reply With Quote
Old 04-04-2019, 02:00 PM   #4
Yorkie mom of 4
Donating YT Member
 
Lovetodream88's Avatar
 
Join Date: Feb 2008
Location: LaPlata, Md
Posts: 22,792
Default

Quote:
Originally Posted by woofwoofwoof View Post
I want to use it to see if maybe it shrinks the lump on my pup
I do not think it will work for that.
__________________
Taylor
My babies Joey, Penny ,Ollie & Dixie
Callie Mae, you will forever be in my heart!
Lovetodream88 is offline   Reply With Quote
Old 04-05-2019, 08:44 AM   #5
♥ Love My Tibbe! ♥
Donating Member
 
yorkietalkjilly's Avatar
 
Join Date: Feb 2011
Location: D/FW, Texas
Posts: 22,140
Default

Until product case studies with peer review are done for its use specifically in dogs, I'd be terrified to use it. The claims of the actual manufacturer as to the ingredients, benefits, safety measures used, toxicity, etc. are all just claims, with no proof as to any side effects or long term use results. For all you know, it could shut your dog's kidneys down one day or give him/her anemia or cancer.

I'd be very careful of using products that have no history of case studies of use/prolonged use or without government oversight and cited peer review. For all you know, some of the ingredients used are cheap, useless grains or filler, toxins or the lab they're mixed, produced, bottled and/or stored in is rodent/insect/pesticide-infested or resides near a chemical plant producing lethal products! Just because the manufacturer produces a lovely bottle of product with labels making beautiful claims doesn't mean the ingredients in it are as stated or actually do anything but produce placebo-effect per statements online or in a magazine that may all/partly be fake or paid for.

I just couldn't do it until I knew a whole lot more about the product's long-term efficacy knowing who paid for and did and commented on the results of the case studies and manufacturer's bona fides.
__________________
Jeanie and Tibbe
One must do the best one can. You may get some marks for a very imperfect answer: you will certainly get none for leaving the question alone. C. S. Lewis
yorkietalkjilly is offline   Reply With Quote
Old 04-05-2019, 09:45 AM   #6
Yorkie mom of 4
Donating YT Member
 
Lovetodream88's Avatar
 
Join Date: Feb 2008
Location: LaPlata, Md
Posts: 22,792
Default

Quote:
Originally Posted by yorkietalkjilly View Post
Until product case studies with peer review are done for its use specifically in dogs, I'd be terrified to use it. The claims of the actual manufacturer as to the ingredients, benefits, safety measures used, toxicity, etc. are all just claims, with no proof as to any side effects or long term use results. For all you know, it could shut your dog's kidneys down one day or give him/her anemia or cancer.

I'd be very careful of using products that have no history of case studies of use/prolonged use or without government oversight and cited peer review. For all you know, some of the ingredients used are cheap, useless grains or filler, toxins or the lab they're mixed, produced, bottled and/or stored in is rodent/insect/pesticide-infested or resides near a chemical plant producing lethal products! Just because the manufacturer produces a lovely bottle of product with labels making beautiful claims doesn't mean the ingredients in it are as stated or actually do anything but produce placebo-effect per statements online or in a magazine that may all/partly be fake or paid for.

I just couldn't do it until I knew a whole lot more about the product's long-term efficacy knowing who paid for and did and commented on the results of the case studies and manufacturer's bona fides.
I’m using it for Callie and she’s like a puppy again and not hurting. The ingredients are listed on the bottle. In AKC family dog magazine I read an article how there are studies being done and the AKC is even paying for some. I disagree that it is as dangerous as you are trying to make it sound. I can’t speak for the pet products because I use human grade and like I said the ingredients are listed on the bottle. I much happier using this then adding another pain medicine which will for a fact effect her liver. Being done by the government and FDA honestly mean nothing much these days considering all the medicines and things they ok that kills people or has serious side effects.
__________________
Taylor
My babies Joey, Penny ,Ollie & Dixie
Callie Mae, you will forever be in my heart!
Lovetodream88 is offline   Reply With Quote
Old 04-06-2019, 11:16 AM   #7
♥ Love My Tibbe! ♥
Donating Member
 
yorkietalkjilly's Avatar
 
Join Date: Feb 2011
Location: D/FW, Texas
Posts: 22,140
Default

Quote:
Originally Posted by Lovetodream88 View Post
I’m using it for Callie and she’s like a puppy again and not hurting. The ingredients are listed on the bottle. In AKC family dog magazine I read an article how there are studies being done and the AKC is even paying for some. I disagree that it is as dangerous as you are trying to make it sound. I can’t speak for the pet products because I use human grade and like I said the ingredients are listed on the bottle. I much happier using this then adding another pain medicine which will for a fact effect her liver. Being done by the government and FDA honestly mean nothing much these days considering all the medicines and things they ok that kills people or has serious side effects.
I remember years back reading in the Dallas Times Herald articles about tons of people using an OTC muscle builder/supplement of some type and it led to serious complications for too many, seem to think it was L-lysine or something but I was a 20-something and that was years back. Series of newspaper articles about it and my sister and I talked about it frequently as she'd taken a portion of a bottle of it. Not to mention, you have NO IDEA what ingredients are actually used, safety record of the drug over long-term use in dogs, the manufacturer or storage facilities unless you have pretty darn reliable empirical evidence you are willing to bet your dog's health on. Just because a magazine article mentions it by no means ensures any drug or supplement safety, if you know how many magazines generate content. And if Hill's Prescription dog food manufacturers can get it wrong, kill many dogs slowly, painfully, think what havoc some of these lesser-known, foreign-based or cheaper manufacturers or their supplies might wreak on unsuspecting dogs' health. Many OTC drugs/supplements contain potentially dangerous ingredients - this is from Google:

Yes. Many supplements contain active ingredients that have strong biological effects in the body. This could make them unsafe in some situations and hurt or complicate your health. For example, the following actions could lead to harmful – even life-threatening – consequences.Nov 29, 2017
__________________
Jeanie and Tibbe
One must do the best one can. You may get some marks for a very imperfect answer: you will certainly get none for leaving the question alone. C. S. Lewis
yorkietalkjilly is offline   Reply With Quote
Old 04-06-2019, 12:04 PM   #8
♥ Love My Tibbe! ♥
Donating Member
 
yorkietalkjilly's Avatar
 
Join Date: Feb 2011
Location: D/FW, Texas
Posts: 22,140
Default

Quote:
Originally Posted by Lovetodream88 View Post
I’m using it for Callie and she’s like a puppy again and not hurting. The ingredients are listed on the bottle. In AKC family dog magazine I read an article how there are studies being done and the AKC is even paying for some. I disagree that it is as dangerous as you are trying to make it sound. I can’t speak for the pet products because I use human grade and like I said the ingredients are listed on the bottle. I much happier using this then adding another pain medicine which will for a fact effect her liver. Being done by the government and FDA honestly mean nothing much these days considering all the medicines and things they ok that kills people or has serious side effects.
While I'm super-wary of OTC drugs for use on my little one, I'm not quite that psycho about myself, as my lifespan is far longer than Tibbe's. Have you ever used CBD oil for your own pain or other symptoms? I've heard so much about its use in humans for pain and I think nausea(have a lot of nausea since the partial colon resection) and am getting more and more interested in using it myself to aid in pain and nausea treatment.

Have you or any subscriber of this thread had or do you know anyone who has used it and did it help joint/nerve pain and were there any side effects" I hate the way my pain medicine makes me feel so I just take it in pieces over time to avoid the head rush, which I'm pretty phobic of.
__________________
Jeanie and Tibbe
One must do the best one can. You may get some marks for a very imperfect answer: you will certainly get none for leaving the question alone. C. S. Lewis
yorkietalkjilly is offline   Reply With Quote
Old 04-06-2019, 03:58 PM   #9
Yorkie mom of 4
Donating YT Member
 
Lovetodream88's Avatar
 
Join Date: Feb 2008
Location: LaPlata, Md
Posts: 22,792
Default

Quote:
Originally Posted by yorkietalkjilly View Post
I remember years back reading in the Dallas Times Herald articles about tons of people using an OTC muscle builder/supplement of some type and it led to serious complications for too many, seem to think it was L-lysine or something but I was a 20-something and that was years back. Series of newspaper articles about it and my sister and I talked about it frequently as she'd taken a portion of a bottle of it. Not to mention, you have NO IDEA what ingredients are actually used, safety record of the drug over long-term use in dogs, the manufacturer or storage facilities unless you have pretty darn reliable empirical evidence you are willing to bet your dog's health on. Just because a magazine article mentions it by no means ensures any drug or supplement safety, if you know how many magazines generate content. And if Hill's Prescription dog food manufacturers can get it wrong, kill many dogs slowly, painfully, think what havoc some of these lesser-known, foreign-based or cheaper manufacturers or their supplies might wreak on unsuspecting dogs' health. Many OTC drugs/supplements contain potentially dangerous ingredients - this is from Google:

Yes. Many supplements contain active ingredients that have strong biological effects in the body. This could make them unsafe in some situations and hurt or complicate your health. For example, the following actions could lead to harmful – even life-threatening – consequences.Nov 29, 2017
I think you misunderstood me I did not get my information from a magazine article. I did learn in the article that ones study has been done and the AKC is paying for it. I am not using some cheap product what I am buying is human grade which has to list the ingredients and on their website of the brand I buy has a specific certification of analysis. You don’t know what’s in an aspirin for sure either but bet you take one when you have a headache. CBD oil is very safe and is much better for Callie’s liver then the pain medicine she would needed upped if it weren’t for the CBD oil. I did not go out and just buy some and give it to her blindly. I did A LOT of research on it and even talked to my vet about it. I would never do anything to harm Callie just help her and make her better. If only you could see the difference it has made then maybe you would understand.
__________________
Taylor
My babies Joey, Penny ,Ollie & Dixie
Callie Mae, you will forever be in my heart!
Lovetodream88 is offline   Reply With Quote
Old 04-06-2019, 05:08 PM   #10
♥ Love My Tibbe! ♥
Donating Member
 
yorkietalkjilly's Avatar
 
Join Date: Feb 2011
Location: D/FW, Texas
Posts: 22,140
Default

Quote:
Originally Posted by Lovetodream88 View Post
I think you misunderstood me I did not get my information from a magazine article. I did learn in the article that ones study has been done and the AKC is paying for it. I am not using some cheap product what I am buying is human grade which has to list the ingredients and on their website of the brand I buy has a specific certification of analysis. You don’t know what’s in an aspirin for sure either but bet you take one when you have a headache. CBD oil is very safe and is much better for Callie’s liver then the pain medicine she would needed upped if it weren’t for the CBD oil. I did not go out and just buy some and give it to her blindly. I did A LOT of research on it and even talked to my vet about it. I would never do anything to harm Callie just help her and make her better. If only you could see the difference it has made then maybe you would understand.
Yes, I did misunderstand about the article and I totally believe CBD oil is helping Callie. I'm not trying to upset you and certainly not pick a fight over CBD oil but I'm just very, very cautious about drugs I give Tibbe, just as I would my child, just having to have more research and oversight before I use something on him than there is on CBD oil use in dogs, particularly toy dogs like Tibbe. I, and my parents and older sister, have taken Bayer aspirin for years, heartened once we learned of them, dozens of Bayer aspirin research studies and dozens of years of good empirical evidence, with long-term records of hospital uses, physicians prescribing it since it was introduced in 1899, to show that if taken as prescribed, it's safe for most humans in most cases and efficacious when properly prescribed and used. But I can't say the same of CBD oil. CBD oil hasn't been comparatively sold, prescribed, researched or used as widely in this country as Bayer aspirin or long enough for any reasonable comparison, let alone ingredient purity/toxicity long-term safety comparisons; and I doubt if many know much of its many manufacturers' safety history or ingredient sourcing.

Until there is more widely-recognized research of any product on dogs and more oversight over the CBD oil industry, I just cannot willing decide, under any circumstances, to give my one and only baby, the one dog that means everything in this world to me, something that may be helping now but could, possibly, over time, do something dreadful such as ulcerate his stomach lining through, his liver or kidneys or even give him cancer, as improbable as that may sound now to CBD oil fanciers. One day, if more than one vet specialist pronounced Tibbe were dying, I might try something out of desperation if it seemed to help him. If he were dying anyway, I can see taking the risk. And I think I might take the risk for my own use.

Just Googled it and CBD oil is against the law in Texas so I won't be able to use it for myself until and if it's legislated for use here. Hopefully if and when it is legislated saleable here, somehow they will mandate some type of regulatory oversight to help ensure product safety. Really glad it is working for your elder girl, Callie, and really, truly hope CBD oil continues to serve everyone taking it well and safely as there seems to be so much hope and help in what I've read and heard.
__________________
Jeanie and Tibbe
One must do the best one can. You may get some marks for a very imperfect answer: you will certainly get none for leaving the question alone. C. S. Lewis

Last edited by yorkietalkjilly; 04-06-2019 at 05:10 PM.
yorkietalkjilly is offline   Reply With Quote
Old 04-06-2019, 05:56 PM   #11
Yorkie mom of 4
Donating YT Member
 
Lovetodream88's Avatar
 
Join Date: Feb 2008
Location: LaPlata, Md
Posts: 22,792
Default

Quote:
Originally Posted by yorkietalkjilly View Post
Yes, I did misunderstand about the article and I totally believe CBD oil is helping Callie. I'm not trying to upset you and certainly not pick a fight over CBD oil but I'm just very, very cautious about drugs I give Tibbe, just as I would my child, just having to have more research and oversight before I use something on him than there is on CBD oil use in dogs, particularly toy dogs like Tibbe. I, and my parents and older sister, have taken Bayer aspirin for years, heartened once we learned of them, dozens of Bayer aspirin research studies and dozens of years of good empirical evidence, with long-term records of hospital uses, physicians prescribing it since it was introduced in 1899, to show that if taken as prescribed, it's safe for most humans in most cases and efficacious when properly prescribed and used. But I can't say the same of CBD oil. CBD oil hasn't been comparatively sold, prescribed, researched or used as widely in this country as Bayer aspirin or long enough for any reasonable comparison, let alone ingredient purity/toxicity long-term safety comparisons; and I doubt if many know much of its many manufacturers' safety history or ingredient sourcing.

Until there is more widely-recognized research of any product on dogs and more oversight over the CBD oil industry, I just cannot willing decide, under any circumstances, to give my one and only baby, the one dog that means everything in this world to me, something that may be helping now but could, possibly, over time, do something dreadful such as ulcerate his stomach lining through, his liver or kidneys or even give him cancer, as improbable as that may sound now to CBD oil fanciers. One day, if more than one vet specialist pronounced Tibbe were dying, I might try something out of desperation if it seemed to help him. If he were dying anyway, I can see taking the risk. And I think I might take the risk for my own use.

Just Googled it and CBD oil is against the law in Texas so I won't be able to use it for myself until and if it's legislated for use here. Hopefully if and when it is legislated saleable here, somehow they will mandate some type of regulatory oversight to help ensure product safety. Really glad it is working for your elder girl, Callie, and really, truly hope CBD oil continues to serve everyone taking it well and safely as there seems to be so much hope and help in what I've read and heard.
Callie is almost 12 and has significant health issues so long term effects are not really an issue. Right now it’s about keeping her happy and comfortable. My dogs are my life and I would never do anything to harm them ever. I probably would not use it on a long term basis with the younger ones but I guess it would depend on the situation. CBD oil with out THC is legal in every state. If you want it with THC that’s different.
__________________
Taylor
My babies Joey, Penny ,Ollie & Dixie
Callie Mae, you will forever be in my heart!
Lovetodream88 is offline   Reply With Quote
Old 04-06-2019, 06:39 PM   #12
♥ Love My Tibbe! ♥
Donating Member
 
yorkietalkjilly's Avatar
 
Join Date: Feb 2011
Location: D/FW, Texas
Posts: 22,140
Default

I didn't know CBD oil w/out THC is legal in Texas. That being the case, I might try it on myself but just couldn't on Tibbe until there has been more research.

Just interested, would you or do you know of anyone who would use CBD oil on your/their human baby?

FYI, on another thread where I was talking about the dangers of OTC manufactured drugs, might have been one of your threads, I found several links to online articles about the extremely serious, even deadly, situation I was remembering. I recall reading about it and talking to my sister about it, as she had taken some of it. Heck, now that I think back, seems like everyone was taking amino acid, protein powder and muscle-building supplements to help build muscle, as those were the days of Jane Fonda's workout videos and athletes were downing it like candy. Was also about the time many athletes began using andro, so it was about 20 years later than I'd thought.

But here is one of the links on the L-tryptophan OTC supplement drug. One article I read stated 1500 cases, 37 deaths before L-tryptophan was recalled for a time. You can also find research on it on Google Scholar. I'd be interested in researching the safety of CBD oil in dogs. Taking amino acids, proteins was a very big deal to those trying to keep up with workouts, building muscle and stamina at the time. Billie, my sister, bought hers at GNC at the mall. Below is the link to one of the many online articles and the last copy of a statement posted from Google Search Answers I posted on that thread.

https://rarediseases.org/rare-diseas...lgia-syndrome/

Yes. Many supplements contain active ingredients that have strong biological effects in the body. This could make them unsafe in some situations and hurt or complicate your health. For example, the following actions could lead to harmful – even life-threatening – consequences.Nov 29, 2017
__________________
Jeanie and Tibbe
One must do the best one can. You may get some marks for a very imperfect answer: you will certainly get none for leaving the question alone. C. S. Lewis
yorkietalkjilly is offline   Reply With Quote
Old 04-06-2019, 07:29 PM   #13
Yorkie mom of 4
Donating YT Member
 
Lovetodream88's Avatar
 
Join Date: Feb 2008
Location: LaPlata, Md
Posts: 22,792
Default

Quote:
Originally Posted by yorkietalkjilly View Post
I didn't know CBD oil w/out THC is legal in Texas. That being the case, I might try it on myself but just couldn't on Tibbe until there has been more research.

Just interested, would you or do you know of anyone who would use CBD oil on your/their human baby?

FYI, on another thread where I was talking about the dangers of OTC manufactured drugs, might have been one of your threads, I found several links to online articles about the extremely serious, even deadly, situation I was remembering. I recall reading about it and talking to my sister about it, as she had taken some of it. Heck, now that I think back, seems like everyone was taking amino acid, protein powder and muscle-building supplements to help build muscle, as those were the days of Jane Fonda's workout videos and athletes were downing it like candy. Was also about the time many athletes began using andro, so it was about 20 years later than I'd thought.

But here is one of the links on the L-tryptophan OTC supplement drug. One article I read stated 1500 cases, 37 deaths before L-tryptophan was recalled for a time. You can also find research on it on Google Scholar. I'd be interested in researching the safety of CBD oil in dogs. Taking amino acids, proteins was a very big deal to those trying to keep up with workouts, building muscle and stamina at the time. Billie, my sister, bought hers at GNC at the mall. Below is the link to one of the many online articles and the last copy of a statement posted from Google Search Answers I posted on that thread.

https://rarediseases.org/rare-diseas...lgia-syndrome/

Yes. Many supplements contain active ingredients that have strong biological effects in the body. This could make them unsafe in some situations and hurt or complicate your health. For example, the following actions could lead to harmful – even life-threatening – consequences.Nov 29, 2017
CBD oil is definitely different then a protein body builder supplement. I have many stories of people using CBD oil on kids with cancer and kids with constant seizure issues. My dogs are my babies so yes would be the answer especially if I was in the situations many parents are in when they do it. All studies on it show it’s very safe and almost impossible to OD on. This is not a new thing it just has gotten more press lately.
__________________
Taylor
My babies Joey, Penny ,Ollie & Dixie
Callie Mae, you will forever be in my heart!
Lovetodream88 is offline   Reply With Quote
Old 04-06-2019, 07:47 PM   #14
♥ Love My Tibbe! ♥
Donating Member
 
yorkietalkjilly's Avatar
 
Join Date: Feb 2011
Location: D/FW, Texas
Posts: 22,140
Default

Do you mind me asking what you are giving little Callie this drug for and if you used regulated prescription drugs first to no avail?
__________________
Jeanie and Tibbe
One must do the best one can. You may get some marks for a very imperfect answer: you will certainly get none for leaving the question alone. C. S. Lewis
yorkietalkjilly is offline   Reply With Quote
Old 04-06-2019, 08:06 PM   #15
♥ Love My Tibbe! ♥
Donating Member
 
yorkietalkjilly's Avatar
 
Join Date: Feb 2011
Location: D/FW, Texas
Posts: 22,140
Default

The final studies on the epidemic from the non-regulated, non-prescription OTC drug L-tryptophan, an OTC amino acid supplement available at nutrition and pharmacies who sell OTC drugs, revealed the causes for the illnesses/deaths:

Causes
Although almost all cases of eosinophilia-myalgia syndrome in the 1989 epidemic were traced back to ingestion of contaminated L-tryptophan manufactured by a single company, namely Showa Denko K.K. (Tokyo, Japan), a large petrochemical company, the precise contaminant causing the disease is still unknown.

There had been isolated cases of EMS diagnosed before the epidemic of 1989 and there have been after, as well. The isolated cases of EMS diagnosed before the epidemic of 1989 were attributed to L-tryptophan dietary supplements. The isolated cases of EMS that are currently being diagnosed are attributed to L-tryptophan or 5-HTP dietary supplements. During the time that L-tryptophan was taken off the market, the closely related dietary supplement 5-hydroxytryptophan (5-HTP) was used as a substitute, and it continues to be so used. The amino acid 5-HTP is found on the metabolic pathway that converts the essential amino acid L-tryptophan to the neurotransmitter serotonin. Because serotonin helps to regulate sleep and mood (among other things), it is thought that ingesting L-tryptophan or 5-HTP, thus purportedly improving sleep and mood, will increase this neurotransmitter.

The National Eosinophilia Myalgia Syndrome Network (NEMSN), for the past several years, has also been receiving reports from people who have developed EMS-like symptoms soon after ingesting manufactured L-tryptophan, 5-HTP, or other products containing L-tryptophan or 5-HTP, such as certain body building products, weight loss supplements, and sleep aids.

Affected Populations
Eosinophilia-myalgia syndrome was identified as an epidemic in 1989 after three people in New Mexico were identified with the disorder. The exact incidence of eosinophilia-myalgia syndrome is unknown. One estimate indicates that anywhere from 5,000-10,000 people developed the disorder during the epidemic. Most reported individuals are females and from the United States. However, eosinophilia-myalgia syndrome has been reported in other countries as well including Germany, Canada and the United Kingdom.

Related Disorders
Symptoms of the following disorders can be similar to those of eosinophilia-myalgia syndrome. Comparisons may be useful for a differential diagnosis.

Eosinophilic fasciitis is a rare disorder characterized by inflammation of the tough band of fibrous tissue beneath the skin (fascia). The arms and legs are most often affected. Inflammation is caused by the abnormal accumulation of certain white blood cells including eosinophils in the fascia. Eosinophilic fasciitis eventually causes the skin to swell and slowly thicken and harden (induration). The disorder most commonly affects middle-aged adults. The exact cause of eosinophilic fasciitis is unknown. Some researchers believe that eosinophilic fasciitis is a variant of scleroderma (systemic sclerosis), an autoimmune connective tissue disorder characterized by hardening of the skin. Eosinophilic fasciitis commonly afflicted EMS patients. (For more information on this disorder, choose “eosinophilic fasciitis” as your search term in the Rare Disease Database.)

Toxic oil syndrome is a rare disorder that occurred in Spain in the early 1980s. Affected individuals developed a variety of symptoms including shortness of breath (dyspnea), cough, chest pain, headaches, and fever. Additional symptoms occurred in some cases including abdominal pain, difficulty swallowing (dysphagia), nausea, a skin rash, itching (pruritus), a rapid heartbeat (tachycardia), an abnormally enlarged liver (hepatomegaly) and an abnormally enlarged spleen (splenomegaly). Eventually, affected individuals develop severe muscle pain and cramps. Affected individuals also had abnormally high levels of eosinophils (a type of white blood cell) in the body (eosinophilia). Toxic oil syndrome was caused by rapeseed oil, which was intended for industrial use, but fraudulently sold as olive oil. Researchers believe that toxins found in the rapeseed oil (as part of the refinement process), such as fatty acid compounds (anilides), caused the symptoms of the disorder. However, as with EMS, the cause of the toxic oil syndrome remains a mystery.

Eosinophilic disorder is a general term for any disorder characterized by infiltration of the skin and tissue by a certain type of white blood cell called eosinophils, including disease resulting from arthropod bites, infections, and drug reactions. Churg-Strauss syndrome, hypereosinophilic syndrome and eosinophilic cellulitis are examples of disorders characterized by elevated levels of eosinophils. (For more information on these disorders, choose the specific disorder name as your search term in the Rare Disease Database.)

Diagnosis
EMS is a syndrome with multiple clinical presentations and variable severity. The first clinical reports showed that most patients developed profound eosinophilia and severe myalgias. Further, other symptoms included joint pains, weakness or fatigue, difficulty breathing or cough, rash, headache, peripheral edema (swelling), fever and abnormal tingling sensations. Most patients also showed an elevation of an enzyme called serum aldolase, which is an indicator of muscle damage. About one-half of the patients had abnormal liver function tests.

Clinical and histopathological findings of EMS overlap those of eosinophilic fasciitis a fibrotic syndrome characterized by tender swelling and hardening of subcutaneous tissues especially in arms and legs.

There are no medical tests to definitively diagnose EMS. Many physicians lack knowledge of EMS, and therefore, patients may be diagnosed with diseases that have overlapping symptoms, such as fibromyalgia, chronic fatigue syndrome, lupus, arthritis, fasciitis, and other autoimmune or neuromuscular disorders with similar symptoms. Criteria for the diagnosis have been described that are useful.

Standard Therapies
Treatment

There are no peer-reviewed guidelines for the standard of care of EMS patients. Because of the variety and diversity of how EMS manifests, patients are treated based on their individual symptoms and may be prescribed muscle relaxants, analgesics, and diuretics.

High doses of corticosteroids may help reduce inflammation, However, most researchers have concluded that this course of treatment does not reduce the severity or duration of EMS symptoms.

In the acute phase, patients who have intense muscle pain and cramps may need to limit or avoid strenuous physical activity. Some patients have required hospitalization. In the chronic phase, patients who keep as physically active as possible seem to do better than others.

Investigational Therapies
Information on current clinical trials is posted on the Internet at www.clinicaltrials.gov . All studies receiving U.S. government funding, and some supported by private industry, are posted on this government web site.

For information about clinical trials being conducted at the NIH Clinical Center in Bethesda, MD, contact the NIH Patient Recruitment Office:

Tollfree: (800) 411-1222
TTY: (866) 411-1010
Email: prpl@cc.nih.gov

Some current clinical trials also are posted on the following page on the NORD website: https://rarediseases.org/for-patient...t-recruitment/

For information about clinical trials sponsored by private sources, contact: www.centerwatch.com.

For information about clinical trials conducted in Europe, contact: https://www.clinicaltrialsregister.eu/

NORD Member Organizations
American Partnership for Eosinophilic Disorders (APFED)
PO Box 29545
Atlanta, GA 30359
Phone: (713) 493-7749
Website: http://www.apfed.org
National Eosinophilia Myalgia Syndrome Network
P O Box 4171
Monitor Station
West New York, NJ 07093 USA
Phone: (201) 868-5791
Email: nemsntalk@aol.com, nemsnnewseditor@gmail.com
Website: home | National Eosinophilia-Myalgia Syndrome Network
Other Organizations
Campaign Urging Research for Eosinophilic Disease (CURED)
PO Box 32
Lincolnshire, IL 60069
Phone: (847) 361-3292
Email: ellyn@curedfoundation.org
Website: http://www.curedfoundation.org
Centers for Disease Control and Prevention
1600 Clifton Road NE
Atlanta, GA 30333
Phone: (404) 639-3534
Toll-free: (800) 232-4636
Email: cdcinfo@cdc.gov
Website: http://www.cdc.gov/

References
JOURNAL ARTICLES
Fernstrom JD. Effects and side effects associated with the non-nutritional use of tryptophan by humans. J Nutr. 2012;142:2236S-2244S. http://www.ncbi.nlm.nih.gov/pubmed/23077193

Valent P, Klion AD, Rosenwasser LJ, et al. ICON: eosinophil disorders. World Allergy Organ J. 2012;5:174-181. http://www.ncbi.nlm.nih.gov/pubmed/23282419

Allen JA, Peterson A, Sufit R, et al. Post-epidemic eosinophilia-myalgia syndrome associated with L-tryptophan. Arthritis Rheum. 2011;63:3633-3639. http://www.ncbi.nlm.nih.gov/pubmed/21702023

Margolin L. Non-L-tryptophan related eosinophilia-myalgia syndrome with hypoprotinemia and hypoalbuminemia. J Rheumatol. 2003;30:628-629. http://www.ncbi.nlm.nih.gov/pubmed/12610828

Continued next post:
__________________
Jeanie and Tibbe
One must do the best one can. You may get some marks for a very imperfect answer: you will certainly get none for leaving the question alone. C. S. Lewis
yorkietalkjilly is offline   Reply With Quote
Reply

Bookmarks



Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is Off
HTML code is Off
Trackbacks are On
Pingbacks are On
Refbacks are Off




Google
 

SHOP NOW: Amazon :: eBay :: Buy.com :: Newegg :: PetStore :: Petco :: PetSmart


All times are GMT -8. The time now is 02:56 AM.


Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2021, vBulletin Solutions, Inc.
Copyright ©2003 - 2018 YorkieTalk.com
Privacy Policy - Terms of Use

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499 500 501 502 503 504 505 506 507 508 509 510 511 512 513 514 515 516 517 518 519 520 521 522 523 524 525 526 527 528 529 530 531 532 533 534 535 536 537 538 539 540 541 542 543 544 545 546 547 548 549 550 551 552 553 554 555 556 557 558 559 560 561 562 563 564 565 566 567 568 569 570 571 572 573 574 575 576 577 578 579 580 581 582 583 584 585 586 587 588 589 590 591 592 593 594 595 596 597 598 599 600 601 602 603 604 605 606 607 608 609 610 611 612 613 614 615 616 617 618 619 620 621 622 623 624 625 626 627 628 629 630 631 632 633 634 635 636 637 638 639 640 641 642 643 644 645 646 647 648 649 650 651 652 653 654 655 656 657 658 659 660 661 662 663 664 665 666 667 668 669 670 671 672 673 674 675 676 677 678 679 680 681 682 683 684 685 686 687 688 689 690 691 692 693 694 695 696 697 698 699 700 701 702 703 704 705 706 707 708 709 710 711 712 713 714 715 716 717 718 719 720 721 722 723 724 725 726 727 728 729 730 731 732 733 734 735 736 737 738 739 740 741 742 743 744 745 746 747 748 749 750 751 752 753 754 755 756 757 758 759 760 761 762 763 764 765 766 767 768 769 770 771 772 773 774 775 776 777 778 779 780 781 782 783 784 785 786 787 788 789 790 791 792 793 794 795 796 797 798 799 800 801 802 803 804 805 806 807 808 809 810 811 812 813 814 815 816 817 818 819 820 821 822 823 824 825 826 827 828 829 830 831 832 833 834 835 836 837 838 839 840 841 842 843 844 845 846 847 848 849 850 851 852 853 854 855 856 857 858 859 860 861 862 863 864 865 866 867 868 869 870 871 872 873 874 875 876 877 878 879 880 881 882 883 884 885 886 887 888 889 890 891 892 893 894 895 896 897 898 899 900 901 902 903 904 905 906 907 908 909 910 911 912 913 914 915 916 917 918 919 920 921 922 923 924 925 926 927 928 929 930 931 932 933 934 935 936 937 938 939 940 941 942 943 944 945 946 947 948 949 950 951 952 953 954 955 956 957 958 959 960 961 962 963 964 965 966 967 968 969 970 971 972 973 974 975 976 977 978 979 980 981 982 983 984 985 986 987 988 989 990 991 992 993 994 995 996 997 998 999 1000 1001 1002 1003 1004 1005 1006 1007 1008 1009 1010 1011 1012 1013 1014 1015 1016 1017 1018 1019 1020 1021 1022 1023 1024 1025 1026 1027 1028 1029 1030 1031 1032 1033 1034 1035 1036 1037 1038 1039 1040 1041 1042 1043 1044 1045 1046 1047 1048 1049 1050 1051 1052 1053 1054 1055 1056 1057 1058 1059 1060 1061 1062 1063 1064 1065 1066 1067 1068 1069 1070 1071 1072 1073 1074 1075 1076 1077 1078 1079 1080 1081 1082 1083 1084 1085 1086 1087 1088 1089 1090 1091 1092 1093 1094 1095 1096 1097 1098 1099 1100 1101 1102 1103 1104 1105 1106 1107 1108 1109 1110 1111 1112 1113 1114 1115 1116 1117 1118 1119 1120 1121 1122 1123 1124 1125 1126 1127 1128 1129 1130 1131 1132 1133 1134 1135 1136 1137 1138 1139 1140 1141 1142 1143 1144 1145 1146 1147 1148 1149 1150 1151 1152 1153 1154 1155 1156 1157 1158 1159 1160 1161 1162 1163 1164 1165 1166