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Old 06-24-2010, 07:43 AM   #286
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with dex pancreatitis never noticed back pain it was all abdominal pain through palpatation. He was so uncomfortable he was tossing and turning and could not get comfortable and then massive vomitting over and over so i rushed him in immediately.

They ran bats on dee dee bc she was going on atopica and temarilp and they wanted her liver tested prior to doing any meds since she was a yorkie. They did post bat only first time and it was 73, then they wanted to repeat and do pre and post -pre 3 and post 54 then they wanted scintigraphy done and as soon as they said radioactive dye i said WHOA HOLD ON. I went home stayed up 24 hrs like studying for a college exam and read EVERYTHING on liver disease in dogs and joined two liver groups on yahoo and read every day for months. I nixed the scintigraphy as bats were below 100 and my dog had no symptoms other than skin issues which when the liver is not processing things properly skin can be affected as the toxins excrete through skin if not release through body so it can be a side effect. I put her on low protein diet of 18% protein and had her bats re ran by jean dodds 6 months later and she was pre 3 and post 26 normal being 25 and below so the diet alone was a huge difference. Also at time it was 26 she was on atopica and temarilp for her allergies so the low protein diet alone made a huge difference. I do not do any supplements for her liver as her allergies are the biggest concern I have therefore anything she gets in her mouth I am very cautious of as it can cause a reaction to her. When Jean comes out with her liver cleansing diet dog food which she is working on I will then transition dd on to that.

How is miss daisy today?
Okay. Has she ever been on the low protein diet without the atopica and temarilp?
The only thing I've seen concerning skin and LS/MVD is thin coat... haven't seen the skin issues you described. Not arguing, just thinking out loud.... Mine has no skin issues or allergies... her toxin overload (when it happens) manifests as Hepatic Encephalopathy.

Was she on the fish diet when the BAT was redone?

I'm not real familiar with those drugs. Off to do more research...


And concerning Daisy: Ask your vet about probiotics... might be good for her during and after all the antibiotics...

How is she doing? Sending Hugs and Prayers for you both...
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Old 06-24-2010, 07:54 AM   #287
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Okay. Has she ever been on the low protein diet without the atopica and temarilp?
The only thing I've seen concerning skin and LS/MVD is thin coat... haven't seen the skin issues you described. Not arguing, just thinking out loud.... Mine has no skin issues or allergies... her toxin overload (when it happens) manifests as Hepatic Encephalopathy.

Was she on the fish diet when the BAT was redone?

I'm not real familiar with those drugs. Off to do more research...


And concerning Daisy: Ask your vet about probiotics... might be good for her during and after all the antibiotics...

How is she doing? Sending Hugs and Prayers for you both...
she was on the ivd white fish and potato diet I believe at the time- it was either that or the dd salmon and potato diet - I know dex was on the ivd white fish and potato diet at time he had pancreatitis

Dog Food Reviews - Royal Canin Veterinary Diet IVD Potato and Whitefish - Powered by ReviewPost

It could be the hydrolized diet of purina ha made the difference as she is on soy hydrolized diet now.

yeah read alot on liver and skin definitely can be affected but not a major side effect but since she has thyroid and allergies it all together makes it a nightmare combo

I agree on probiotics as antibiotics kill both good and bad bacteria so adding good back in will help re-balance. I always do 2 hrs after antibiotic in evening so it sits on tummy all night long to get a good balance before doing antibiotics the following evening. It really does help and i double up while on antibiotics as well then i do that for 2 weeks after antibiotic is stopped then back down to normal probiotics - it made a huge difference when dd was on clindamycin - no diarrhea

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Old 06-24-2010, 08:30 AM   #288
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This is really no fault of yours. You couldn't have prevented it no matter what you would/could have done. And, all drugs have side effects, some bad, some not so bad. These types of situations are impossible to predict, even for your vet, without doing thousands of dollars worth of testing, for no apparent reasons. There is no way you could have researched Doxycycline and taken into account all the variables to come up with forseeing this outcome.

In short, almost all liver disease is treated the same way: usually protein restricted diet (less junk for the liver to remove), and homeopathic therapy (liver support: Denamarin or similar medication), and time to allow the liver to heal itself. The Denamarim prevents free-radicals from causing cell death, and helps the liver in cell regeneration.



Did they do a CBC? Were any microcytic cells noted?

Your vet really needs to interpret these results, because certain combinations of these liver enzymes being elevated and how far elevated is what they look at. It is very good that the ALT has dropped considerably. My understanding is that the liver is clearing whatever is affecting it (possible toxin= anything that does not agree with and causes harm to the liver cells).

Something you need to understand: The liver, pancreas, and gall bladder all work closely together. These liver enzymes can indicate a problem in any one of these organs, depending on the combination and elevations. So this can be a major factor in the difficulty of narrowing down the exact cause.

Another thing: toxic plants and steroids (pills or topically applies creams) can affect the ALP.

Has the vet done an ultrasound? This may help to see what's happening with the gall bladder, as stones can cause a blockage and increase ALP, and other organs.

And the big 'C'. We all think about this and no one likes to talk about it, but Please remember that tumors can be benign, and may cause changes which may be detected on an ultrasound.

Secondary hyperparathyroidism can also raise the ALP.

I hope I haven't confused you further. I am still researching alot of this stuff in relation to my own dog, who has LS.

I do know exactly how you are feeling. I was wracking my brain for weeks, maybe months, trying to figure things out, and thinking I hurt my dog by feeding her the wrong food/treats/supplements/not watching her close enough...etc. Panic mode, basically. It's a scary place to be, and no one gives you the answers you are looking for. I even paid the 'Ask-A-Vet' online service!

Please relax a little. I know how these lab numbers can freak a person out. The most you can do, you're doing it. Proper food and meds for liver support.

Liver disease/problems are slow to be diagnosed... it's more a process, where most tests tell you right off what's wrong, like high white cell count means an infection, or specific tests for other disease like Lymes or heartworm, you know right away. Liver stuff is more complicated, and takes a combination of a few different tests, and repeated bloodwork to narrow things down.

And realize too, this may end up as something that needs to be managed, like MVD, where there is no cure, per say, but with proper care, diet, meds, you can maintain a quality and quantity of life. I think this was my major frustration. Tell me what it is so we can fix it. Just know, some things can't be fixed, but you learn how to live with them.

When my Mom visits, she always asks,"Which one is the sick one?" And, so far, I've always been able to say "It's that one, the one running around like a nut, jumping up, wanting to give kisses, bringing the toys out to play, and barking like a maniac!" And she says "Are you sure?"
Thank you for that information.
They have done x rays and found nothing and then an ultra sound no tumors and the adrenals looked normal. Her liver was small though.
She said they cant rule out cushings without further testing and they did not think it was pancreatitus.

Today Daisy is isolating herself in her doggie bed in my room (i boght her this bed when she dislocated her knee)
She came out to eat and did sit on the deck for about 15 min. gets up to ask to be taken out and just acting like she wants to be left alone.
She is on Denosyl for her liver and flagyl for the lime disease and pepcid ac to prevent a stomach ulcer.

I also noticed that she is losing weight and her back leg is worse and it almost looks like the muscle is skinny in kinda indents at the hip. Daisy has been very muscular in the past. She doesn't have strength to jump on the bed and she hates going down the stairs she is very unsure of herself..
I am calling the vet bc I am frankly worried sick.
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Old 06-24-2010, 10:20 AM   #289
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Joyce I am sorry to hear about Daisy's leg - what did the vet say when you called?
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Old 06-24-2010, 10:39 AM   #290
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They said it is the lyme and bc she had a reaction to the doxycycline it was like she was not on an antibiotic during the time of the reaction bc her body was fighting the allergic reaction. Her liver is not working as well so it is hard on her to fight the lyme. I am so worried
I just went and laid next to her and started crying and she was licking my face like crazy, She is just such a sweet loveable dog

I forgot to mention that she had very high cholestral

I don't feed her table scraps so how in the heck did this happen. The only hand outs she gets is veggies and fruit.
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Old 06-24-2010, 11:49 AM   #291
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Have to do some searching, but, in people... Hypothyroidism affects metabolism in such a way as the cholesterol will skyrocket.
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Old 06-24-2010, 12:14 PM   #292
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blackgsd: treatment

What Causes High Cholesterol in Dogs? | eHow.com

Remember I asked about steroids? Cholesterol is a steroid. Increased steroids can cause increases in ALP. The three major isoenzymes that contribute to the total serum ALP are: bone, liver and corticosteroid isoenzymes.
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Old 06-24-2010, 12:28 PM   #293
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Question: Has Daisy ever had a Lyme Disease Vaccine?
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Old 06-24-2010, 01:29 PM   #294
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They said it is the lyme and bc she had a reaction to the doxycycline it was like she was not on an antibiotic during the time of the reaction bc her body was fighting the allergic reaction. Her liver is not working as well so it is hard on her to fight the lyme. I am so worried
I just went and laid next to her and started crying and she was licking my face like crazy, She is just such a sweet loveable dog

I forgot to mention that she had very high cholestral

I don't feed her table scraps so how in the heck did this happen. The only hand outs she gets is veggies and fruit.
I posted links, one has alternative meds for Lymes.

The liver produces cholesterol. Red meat is high in Cholesterol, so a chicken based diet may be best if she tolerates chicken... or fish.
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Old 06-24-2010, 03:31 PM   #295
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I posted links, one has alternative meds for Lymes.

The liver produces cholesterol. Red meat is high in Cholesterol, so a chicken based diet may be best if she tolerates chicken... or fish.
i would do fish as it may work better for liver and cholesterol

dd has hypothyroid and on steroids and bloodwork she gets twice a year she does not have high cholesterol on it. She did not have high cholesterol prior to diagnosis of hypothyroid either. Just trying to throw this out there as maybe it will help

so sorry Joyce I know this is so frustrating but just try to hang in there - what are they thinking of doing for the lyme? I just do not have much experience with lyme and wish i could offer more advice. I know about the liver but the lyme I am clueless KJC hopefully can help you more on this as she was a vet tech and is a good researcher - cmon KJC

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Old 06-24-2010, 03:43 PM   #296
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i would do fish as it may work better for liver and cholesterol

dd has hypothyroid and on steroids and bloodwork she gets twice a year she does not have high cholesterol on it. She did not have high cholesterol prior to diagnosis of hypothyroid either. Just trying to throw this out there as maybe it will help

so sorry Joyce I know this is so frustrating but just try to hang in there - what are they thinking of doing for the lyme? I just do not have much experience with lyme and wish i could offer more advice. I know about the liver but the lyme I am clueless KJC hopefully can help you more on this as she was a vet tech and is a good researcher - cmon KJC
I've been hypothyroid since my teens....never had a cholesterol problem. Had radioactive iodine to destroy my thyroid in 2000, still can't get regulated on thyroid replacement, 2006 my cholesterol shot up to 285 , Endochrinology group found correlation between high TSH and high Cholesterol... online of course... I've always eaten health conciously. Maybe a chronic reaction?

Already posted on lymes...
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Old 06-24-2010, 04:17 PM   #297
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I've been hypothyroid since my teens....never had a cholesterol problem. Had radioactive iodine to destroy my thyroid in 2000, still can't get regulated on thyroid replacement, 2006 my cholesterol shot up to 285 , Endochrinology group found correlation between high TSH and high Cholesterol... online of course... I've always eaten health conciously. Maybe a chronic reaction?

Already posted on lymes...
ok cool you always have such great information sorry you are hypothyroid
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Old 06-25-2010, 05:13 AM   #298
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Question: Has Daisy ever had a Lyme Disease Vaccine?
Daisy had a lyme vaccination once and it almost killed her. She was a mess within 1/2 hr of the vaccination and they gave her antiflammatory med and a cortisone shot.
Daisy has had steriods a few times in her life.(
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Old 06-25-2010, 05:32 AM   #299
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Default update that is good but could of been disaster

st night we had some friends over. Daisy had been in her bed all day except to ask for the door and to eat. I would lay next to her on the floor every now and then but she really wanted to be left alone.

We had our company and they were leaving and someone went out the back door and Daisy bolted out the door. We live near a main road and Daisy is a runner. Well I don't know where all the energy came from but she was running around the yard and we were all trying to catch her. Her leg didn't even seem to bother her and then it happened she bolted for the road and it was dark out I said oh God no!!!! My brother in law and my friends boyfriend ran out in busy traffic and stopped the cars just in time.

Daisy ALMOST got hit by a car

My heart stopped! I was so thankful for two reasons that she was feeling up to running around and that she did not get hit.

Daisy has not pulled an escape act like that in about 8 months. We always have her on a leash but when she was a pup she use to escape bc of teenagers in and out of the house.

After everyone left she acted like she was so proud of herself

She asked for the door about 10 min later and pooped 3 times and they were healthy not loose.

I think she is feeling better and maybe the meds and the diet are kicking in.
Everyone keep praying bc she needs a miracle and Gods angels around her

this morning she is a little tired but I am sure that 15 min run was enough to tire her out. I can remember when she was a puppy my son came home from being out and Daisy got lose at 12:00 am he took a chair and sat in the front yard with a flash light. (we lived in a neighborhood) Woke me up at 2:00 am Mom Daisy is lose I was like when did she get lose he replied 2 hrs ago...............Well to shorten it up we are all running around the neighborhood at 2:00 am calling with flash lights and all of a sudden a wet puppy came and sat infront of me.
I said to my dh she smells like tires........lol no it was a SKUNK she got sprayed smack dab in the face and up her nose.

OMG the whole house stunk and we tried everything to get rid of that smell finally in the morning we took her to the groomers and they got rid of most of it. Except her kisses smelled like skunk for 3 months
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Old 06-25-2010, 05:36 AM   #300
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Oh Daisy ! Well, I'm glad to hear she is showing some sassafrass and spunk - but tell her to not scare her Mama! Mama has been through enough . That little stinker. Pure yorkie. Hugs to you both!
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