I'm getting a dna test done. Then what?? - Page 31 - YorkieTalk.com Forums

yorkietalkjilly · 06-10-2013, 02:16 PM

I haven't by any stretch read all the posts here. Is OP going to post the test and everyone is just waiting to see it?

Teresiana · 06-10-2013, 02:39 PM

I just took a look at my test for Momoko. When I adopted her, I was told that she she was an F1 Morkie. However, when I had the test done, I didn't specify between the purebred/mixed breed/designer dog. I just wanted to see what results would come back. Anyway, here's a link to Momo's test...it will give you a vague idea of how Mars interprets the data:
http://goo.gl/6UHDx

pstinard · 06-10-2013, 03:33 PM

Quote:

Originally Posted by yorkietalkjilly

I haven't by any stretch read all the posts here. Is OP going to post the test and everyone is just waiting to see it?

The short answer is yes. Jen still has questions about the results and what they mean, and she's trying to figure out the best way to go about getting answers. I gave Jen the contact info for customer service at MARS Labs, and also offered the expertise of all of us Yorkietalkers.

yorkietalkjilly · 06-10-2013, 03:40 PM

Quote:

Originally Posted by pstinard

The short answer is yes. Jen still has questions about the results and what they mean, and she's trying to figure out the best way to go about getting answers. I gave Jen the contact info for customer service at MARS Labs, and also offered the expertise of all of us Yorkietalkers.

Good. I'd be very interested to see one of these. I doubt I'd ever need something like this but it's good to know about it and what it will/won't do.

pstinard · 06-10-2013, 03:55 PM

Quote:

Originally Posted by Teresiana

I just took a look at my test for Momoko. When I adopted her, I was told that she she was an F1 Morkie. However, when I had the test done, I didn't specify between the purebred/mixed breed/designer dog. I just wanted to see what results would come back. Anyway, here's a link to Momo's test...it will give you a vague idea of how Mars interprets the data:
http://goo.gl/6UHDx

Wow, MARS went above and beyond the call of duty and gave you a free Designer Dog analysis!

The Principle Component Analysis (PCA) is the heart of the analysis. That's the two pages of graphs with the clusters of dots, each one color coded to represent a particular breed of dog, or the F1 (first generation) cross between a Maltese and Yorkie (Morkie). Momo falls exactly in the center of the cluster for the Morkies in both analyses. They left out the graph of the homozygosity profile for Momo, but gave a verbal description of the results--that Momo has the expected homozygosity/heterozygosity of an F1 Morkie, in other words, that Momo is the result of a cross between a Maltese and a Yorkie, and not the result of a cross between two Morkies. Now I REALLY want to see the results for Minnie, because I'm thinking that maybe they did a free test of breed purity on her DNA once they realized she only had Yorkie DNA in her.

pstinard · 06-10-2013, 04:02 PM

Quote:

Originally Posted by yorkietalkjilly

Good. I'd be very interested to see one of these. I doubt I'd ever need something like this but it's good to know about it and what it will/won't do.

Check out Momo's report that Teresiana posted! For a geneticist, it's like uncorking a bottle of fine wine. (Sorry, I just can't help myself

.) I'm hoping to see something similar for Minnie, but as a purebred Yorkie, of course. Can't wait to see Minnie's report!

pstinard · 06-10-2013, 05:10 PM

Jen emailed me the link to Minnie's test results and asked me to post them with personally identifiable information (full name and address, etc.) removed, and here are the first 4 pages. The last two pages will follow in a separate post. Because the only breed detected in Minnie's DNA was Yorkshire Terrier, they did a FREE purebred test (thanks MARS!). Minnie does indeed test as a purebred Yorkshire Terrier. That said, she does fall on the edges of the Yorkie group in the PCA analysis (the two pages that will be in my next post). In other words, Minnie doesn't fall in the middle of the group of typical Yorkies, but doesn't fall completely outside the group either. I'm sure that the other Yorkies in the MARS database conform reasonably well to breed standards (I sent an email to MARS asking how they chose the Yorkies they use as a DNA standard in their database, but they haven't replied yet). My conclusion is that Minnie's unusual appearance is due to a few single gene mutations that were either carried by her parents (most likely), or arose spontaneously (less likely, but still possible). If anyone has questions, please ask! Jen, I recommend that you send an email to the MARS Lab's customer service along with a photo of Minnie and ask for their explanation of Minnie's appearance as well.

pstinard · 06-10-2013, 05:14 PM

Here are the last two pages of Minnie's DNA test report. These are the heart of the purebred test, the PCA analysis, which I described in my last post. There is a lot of meat in these graphs, so if anyone has questions about what they mean, please ask!

pstinard · 06-10-2013, 05:18 PM

Quote:

Originally Posted by pstinard

Here are the last two pages of Minnie's DNA test report. These are the heart of the purebred test, the PCA analysis, which I described in my last post. There is a lot of meat in these graphs, so if anyone has questions about what they mean, please ask!

Oh, I forgot to mention the homozygosity test. This is a test of how inbred Minnie is. Minnie is more inbred than the average Yorkie in their DNA database, but isn't in the abnormal range (tail of the curve), either.

yorkietalkjilly · 06-10-2013, 05:20 PM

Quote:

Originally Posted by Teresiana

I just took a look at my test for Momoko. When I adopted her, I was told that she she was an F1 Morkie. However, when I had the test done, I didn't specify between the purebred/mixed breed/designer dog. I just wanted to see what results would come back. Anyway, here's a link to Momo's test...it will give you a vague idea of how Mars interprets the data:
http://goo.gl/6UHDx

This site seems to want to download this test. Is it supposed to download to to my computer - not just be there to look at?

lynzy420 · 06-10-2013, 06:05 PM

Quote:

Originally Posted by pstinard

Check out Momo's report that Teresiana posted! For a geneticist, it's like uncorking a bottle of fine wine. (Sorry, I just can't help myself

.) I'm hoping to see something similar for Minnie, but as a purebred Yorkie, of course. Can't wait to see Minnie's report!

There is something incredibly attractive about this statement, I love your enthusiasm for geneticism! lol!!!

pstinard · 06-10-2013, 06:06 PM

Quote:

Originally Posted by yorkietalkjilly

This site seems to want to download this test. Is it supposed to download to to my computer - not just be there to look at?

For me, I could view the report on the website without downloading it. My browser on my PC has a PDF file viewer that allows me to do that. If your browser doesn't have a PDF viewer, you might have to download it in order to view it. I don't know what you need to be able to view it on a smart phone--I seem to remember that it's more difficult...

pstinard · 06-10-2013, 06:09 PM

Quote:

Originally Posted by lynzy420

There is something incredibly attractive about this statement, I love your enthusiasm for geneticism! lol!!!

Thanks!

It's my profession, but it's also my hobby. It's great when something can be both!

lynzy420 · 06-10-2013, 06:16 PM

Ok I read the results and while I'm no geneticist, I can see that she is in the lowest range, but I still just can't see Minnie as a Yorkie, how sad that the breed is being so over bred that we can't even decipher the Yorkie from the Yorkie anymore.

Minnie is beautiful, don't get me wrong, she really is gorgeous, I would have loved to have a pup that looks like her she is so unique...at the end of the day the final analysis yields that Minnie is a Yorkie, the breeder did not lie, but the breeder did knowingly sell a very obvious poor representation of the Yorkie Standard, not sure there is any recourse here.

What say you Pstinard?

auntielaurie · 06-10-2013, 06:48 PM

I had to read this post, not all of it but enough to know the concern about the yorkie not being a yorkie. I'm totally in shock that the DNA came back saying it was indeed a yorkie.
I do breed yorkies and have DNA done on them. I do this for the buyer.
I know there are a lot of "yorkies" that sure don't look like pure breds...and the so called designer dogs..really!
Most all dogs are cute, but you should get what you paid for..
I don't remember if this yorkie is AKC registered but I would NEVER buy one that wasn't..that is a big red flag.

06-10-2013, 02:16 PM	#451
yorkietalkjilly ♥ Love My Tibbe! ♥ Donating Member Join Date: Feb 2011 Location: D/FW, Texas Posts: 22,140	I haven't by any stretch read all the posts here. Is OP going to post the test and everyone is just waiting to see it? __________________ Jeanie and Tibbe One must do the best one can. You may get some marks for a very imperfect answer: you will certainly get none for leaving the question alone. C. S. Lewis

06-10-2013, 02:39 PM	#452
Teresiana Donating YT 500 Club Member Join Date: May 2012 Location: NJ Posts: 2,194	I just took a look at my test for Momoko. When I adopted her, I was told that she she was an F1 Morkie. However, when I had the test done, I didn't specify between the purebred/mixed breed/designer dog. I just wanted to see what results would come back. Anyway, here's a link to Momo's test...it will give you a vague idea of how Mars interprets the data: http://goo.gl/6UHDx __________________ Teresa, Yoshi, Momo & Prima

06-10-2013, 05:10 PM	#457
pstinard YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA Posts: 3,648	Drum roll please... (Minnie's test results, part 1) Jen emailed me the link to Minnie's test results and asked me to post them with personally identifiable information (full name and address, etc.) removed, and here are the first 4 pages. The last two pages will follow in a separate post. Because the only breed detected in Minnie's DNA was Yorkshire Terrier, they did a FREE purebred test (thanks MARS!). Minnie does indeed test as a purebred Yorkshire Terrier. That said, she does fall on the edges of the Yorkie group in the PCA analysis (the two pages that will be in my next post). In other words, Minnie doesn't fall in the middle of the group of typical Yorkies, but doesn't fall completely outside the group either. I'm sure that the other Yorkies in the MARS database conform reasonably well to breed standards (I sent an email to MARS asking how they chose the Yorkies they use as a DNA standard in their database, but they haven't replied yet). My conclusion is that Minnie's unusual appearance is due to a few single gene mutations that were either carried by her parents (most likely), or arose spontaneously (less likely, but still possible). If anyone has questions, please ask! Jen, I recommend that you send an email to the MARS Lab's customer service along with a photo of Minnie and ask for their explanation of Minnie's appearance as well. Attached Thumbnails

06-10-2013, 05:14 PM	#458
pstinard YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA Posts: 3,648	Drum roll please... (Minnie's test results, part 2) Here are the last two pages of Minnie's DNA test report. These are the heart of the purebred test, the PCA analysis, which I described in my last post. There is a lot of meat in these graphs, so if anyone has questions about what they mean, please ask! Attached Thumbnails

06-10-2013, 06:16 PM	#464
lynzy420 Donating YT 3000 Club Member Join Date: Dec 2011 Location: USA Posts: 7,652	Ok I read the results and while I'm no geneticist, I can see that she is in the lowest range, but I still just can't see Minnie as a Yorkie, how sad that the breed is being so over bred that we can't even decipher the Yorkie from the Yorkie anymore. Minnie is beautiful, don't get me wrong, she really is gorgeous, I would have loved to have a pup that looks like her she is so unique...at the end of the day the final analysis yields that Minnie is a Yorkie, the breeder did not lie, but the breeder did knowingly sell a very obvious poor representation of the Yorkie Standard, not sure there is any recourse here. What say you Pstinard? __________________ The Above advice/comments/reviews are my personal opinions based on my own experience/education/investigation and research and you can take them any way you want to......Or NOT!!!

06-10-2013, 06:48 PM	#465
auntielaurie No Longer a Member Join Date: Oct 2006 Location: Onalaska Wa. Posts: 107	I had to read this post, not all of it but enough to know the concern about the yorkie not being a yorkie. I'm totally in shock that the DNA came back saying it was indeed a yorkie. I do breed yorkies and have DNA done on them. I do this for the buyer. I know there are a lot of "yorkies" that sure don't look like pure breds...and the so called designer dogs..really! Most all dogs are cute, but you should get what you paid for.. I don't remember if this yorkie is AKC registered but I would NEVER buy one that wasn't..that is a big red flag.