Originally Posted by Buster Brown (Post 3750925)

I did some research these site might help especially UC Davis. You do so much research LadyJane you may all ready have read these. Best wishes
Bacterial resistance to antimicrobials: From the Golden Age to the Bronze Age of antibiotic use - Veterinary Medicine

UC Davis School of Veterinary Medicine - Research Units

Antimicrobial Use Guidelines for Treatment of Urinary Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases

Originally Posted by ladyjane (Post 3750710)

Gabby has had an ongoing problem with UTIs which is very common with paralyzed pups. She has taken one antibiotic after another...diet changes have been done....just cannot get a handle on it. Yesterday I got the awful news that she has two resistant bacteria in her bladder. MRSA is one. I am just sick over this because if we cannot get rid of a normal one, I doubt we will get control of this. :( The problem is that her bladder must be expressed and it is not emptying normally. :( I have spoken with my vet and others and my concern now is what Gabby's quality of life is. She hates the meds, she has a problem many days with her appetite probably due to the meds. I also don't want to think about what happens if this gets out of control and goes to the kidneys and the rest of her body. :( My vet had spoken with the specialist about this previously and we were hoping to get rid of the UTI so that Gabby could be started on a med that would hopefully prevent UTIs. We have never been able to clear it so that did not happen. My vet is going to consult with them again today to see what options are left.
This is horrible for me. I feel just sick over it all. I do not want Gabby to be sick...she is my main concern. :(
She and I could really use your prayers.

Originally Posted by ladyjane (Post 3751375)

My vet spoke with the specialist and we are now waiting for the MIC (minimum inhibatory concentration test) to be completed. His suggestion was to use that as a guide for treatment. The eColi is resistant to everything but Tetracycline and Primor...but even those are not really effective against it. Hopefully when the MIC is back whatever antibiotic the staph is not resistant to will also work for the eColi. There really is nothing else suggested at this point. Our plan is to try and pray a lot....if we cannot get rid of this it will eventually go to her kidneys and then systemic. Very depressing. BUT...I am hopeful.

Originally Posted by 107barney (Post 3751382)

I hope the MIC comes back with a guide and that there is something. I'm sorry it isn't more hopeful but this is actually good news in light of what your vet was saying yesterday. I will pray for little Gabby.

Originally Posted by Furbaby Friend (Post 3751436)

I got this notification in my e-mail about Gabby and signed in special to let you know that I am praying for her with all my might! I've been MIA for a loooong time for various reasons, but could not stay away when I saw this. Please keep us posted about Gabby. ::hugs to you::

Originally Posted by ladyjane (Post 3751375)

My vet spoke with the specialist and we are now waiting for the MIC (minimum inhibatory concentration test) to be completed. His suggestion was to use that as a guide for treatment. The eColi is resistant to everything but Tetracycline and Primor...but even those are not really effective against it. Hopefully when the MIC is back whatever antibiotic the staph is not resistant to will also work for the eColi. There really is nothing else suggested at this point. Our plan is to try and pray a lot....if we cannot get rid of this it will eventually go to her kidneys and then systemic. Very depressing. BUT...I am hopeful.

Originally Posted by lelemommy (Post 3751843)

I'm so sorry little Gabby is sick. Sending prayers for u Linda and Gabby. I know from being a foster parent to children, u put your heart and soul into their well being. I don't know you personally, but from what I have read on here that is what u do.

You and Gabby will be in my thoughts and prayers.

Originally Posted by ladyjane (Post 3752323)

Thank you so much all of you for your kind words...and for prayers for Gabby.

The results came back on the Staph infection and the one drug that will work is Amikacin. It is an injectable antibiotic and she will need to go to the vet daily for 2-3 weeks. My vet was off today so her partner called me...they will confer tomorrow to iron out the plan; but I think it will end up being given intravenously. It can be given subcutaneously, but he said it burns. I do not want her to have any ill effects...if giving it IV will be easier on her, that is what I will want for her. It is a drug that can cause some issues so she will be monitored closely. At this point we have no choice. She could end up in renal failure from the treatment, but will definitely have renal issues if this infection is not cleared up.

We are also waiting on further testing to see if perhaps the Amikacin will work for the E.coli infection.

I will post more tomorrow when I know exactly what my vet wants to do.

Originally Posted by ladyjane (Post 3759875)

I forgot to update. My vet spoke with one of the Internal Med vets at A&M and they suggested an xray to make sure that bladder stones were not present. She also called a different lab to see if they could do a sensitivity test that would include Nitrofurantoin and they can. So, an xray was done on Monday and was negative. She had a cysto and the urine was sent to the other lab.
So, we are still playing the waiting game. I am hopeful that we will get to the bottom of this soon...I hate that she has this awful UTI. :(

Originally Posted by TxVicki (Post 3760150)

Originally Posted by ladyjane (Post 3760159)

Good news for Gabby!!! My vet just called to give me the results of the urine culture and there is NO MRSA!! My first thought was "who do I believe"" .. but as I digested this information it occurred to me that IF it was there it would have shown up. My guess is there was a cross contamination in the first lab. I am horrified when I think of where our conversation was going last week.

The plan now is for her to start on Nitrofurantoin q8 for 2 weeks or longer...all will depend on urine c&s coming up negative. We will test her at 2 weeks to see how it is going.

Doing a Happy Dance here!! :)

:happyboun:happyboun:happyboun:happyboun

Originally Posted by roseslevi (Post 3760161)

Best Damn Christmas present I could have asked for! Thank god!

Originally Posted by ladyjane (Post 3760165)

I hear that! My vet said the same thing. I am still concerned, but honestly I don't see how they could miss it if it was there. Had to be an error in the first one.

Originally Posted by hartygirl (Post 3760180)

I'll be thinking of Gabbers, I'm still remembering the way she was so responsive when we had cupcakes at the show! Her little face and nose were the cutest thing ever. She has the heart and determination of a warrior, anyone that gets to meet her can see that. So many people care about her I know she feels the love.

Originally Posted by ladyjane (Post 3760159)

Good news for Gabby!!! My vet just called to give me the results of the urine culture and there is NO MRSA!! My first thought was "who do I believe"" .. but as I digested this information it occurred to me that IF it was there it would have shown up. My guess is there was a cross contamination in the first lab. I am horrified when I think of where our conversation was going last week.

The plan now is for her to start on Nitrofurantoin q8 for 2 weeks or longer...all will depend on urine c&s coming up negative. We will test her at 2 weeks to see how it is going.

Doing a Happy Dance here!! :)

:happyboun:happyboun:happyboun:happyboun