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04-08-2015, 08:14 PM | #61 | |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
Posts: 27,450
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04-08-2015, 08:17 PM | #62 |
Don't Litter Spay&Neuter Donating Member Join Date: Jan 2009 Location: So Cal
Posts: 9,874
| More Specific Information Saliva is a source of body fluid for detection of an immune response to bacterial, food, and other antigens present in the oral cavity and gastrointestinal tract. Indeed, salivary antibody induction has been widely used as a model system to study secretory responses to ingested material, primarily because saliva is an easy secretion to collect and analyze. It seems to be a general feature that salivary IgA antibodies can be induced in a variety of species in the absence of serum antibodies. This has been demonstrated after immunization with particulate bacterial antigens in humans that could selectively induce an immune response to Streptococcus mutans by oral administration of the antigen. This route of administration resulted only in antibody production in saliva and not in serum. Similar mucosal immune response in the form of saliva IgA did occur in monkeys, rabbits, rats, and mice after oral administration of Streptococcus mutans, Staphylococcus or different viral antigens and peptides. References Kiyono H, Kweon M N, Hiroi T, Takahashi I. The mucosal immune system: from specialized immune defense to inflammation and allergy. Acta Odntol Scand 59:145, 2001. Kanda M, Inove H, Fukuizumi T, Tsujisawa T, Tominaga K, Fukuda J. Detection and rapid increase of salivary antibodies to Staphylococcus lentus and indigenous bacterium in rabbit saliva, through a single tonsillar, Application of bacterial cells. Oral Microbiol Immunol 16:257, 2001. Zee K Y, Samaranayake L P, Attstrom R. Salivary Immunoglobulin A levels in rapid and slow plaque formers: A pilot study. Microbio S 106 Suppl 2:81, 2001. Plante M, Jones T, Allard F, Torossian K, Gauthier J, St-Felix N, White G L, Lowell G H, Burt D S. Nasal immunization with subunit proteosome influenza vaccines induces serum HAI, mucosal IgA and protection against influenza challenge. Vaccine 20:218, 2002. Kraft S C, Rothbert R M, Kramer C M. Gastric output and circulating anti-BSA in adults. Clin and Exp Immuno 2:321-326, 1967. Kagnoff M F. Effects of antigen feeding on intestinal and systemic immune responses. I. Priming of precursor cytotoxic T-cells by antigen feeding. J Immunol 120:395-399, 1978. Challacombe S J, The induction of secretory IgA responses in: food allergy and intolerance edited by Brostoff J, Challacombe S J, published by W. B. Sanders Eastborne England, 1987. Davies A. An investigation in to the serological properties of dysentery stools. Lancet 203:1009-1012, 1922. Montrien B de, Serre. Etudes des immunoglobulins salivaires aptes vaccination locale antistreptococcique. Pathol Biol (Paris) 22:305-312, 1974. McGhee J R, Michalek S M, Webb J et al., Effective immunity to dental caries: protection of gnotobiotic rats by local immunization with Streptococcus mutants. J Immuno 114:300-305, 1975. Krasse B, Gahnberg L, Bratthall D. Antibodies reacting with Streptococcus mutants in secretion from minor salivary glands in humans. Adv Exp Med Biol 107:349-354, 1978. Husband A M, Gowens J L. The origin and antigen-dependent distribution of IgA containing cells in the intestine. J Exp Med 148:1146-1160, 1978. Mesenteric J, McGhee J R, Arnold R R. Selective induction of an immune response in external secretions by ingestion of bacterial antigen. J Clin Invest 61:731-737, 1978. Walker W A, Isselbacher K J. Intestinal antibodies. New Engl J Med 297:767-773, 1977.
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04-08-2015, 08:20 PM | #63 |
Don't Litter Spay&Neuter Donating Member Join Date: Jan 2009 Location: So Cal
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| Post #58, 59, 60 & 62 are from Dr.Dodds' Benefits of Salivary vs Serum Food Intolerance Test I had to copy & paste from a word document.
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04-09-2015, 04:35 AM | #64 |
T. Bumpkins & Co. Donating YT Member Join Date: Dec 2008 Location: New England
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| There's no doubt you can test for antibodies by anestizing a dog and doing a biopsy as is done with a scope. The theory this somehow makes its way into saliva is a huge stretch that no one but Dodds and her followers buy into. Taken from Skeptvet -- "There is no research to suggest that the saliva testing is useful for identifying food allergies. It is sold based on questionable theory and anecdotes, which have little evidentiary value. And as far as uncontrolled testing, at least one dermatologist has run the test in dogs with confirmed food allergies responsive to diet change, and the test results were highly inaccurate."
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04-09-2015, 05:39 AM | #65 | |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
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I'm almost afraid to mention it, but Dr. Dodds recently published a book titled "Canine Nutrigenomics." It is a speculative work that has just enough real facts thrown in to deceive the less discerning reader. And of course it promotes the Nutriscan test. I read about 84 pages of the book for free in Google Books online, and all it did was make me furious. Among her scholarly discussions of DNA, epigenetics, and the immune system, she throws in unproven dietary recommendations such as bee pollen and royal jelly. Here is what WebMD has to say about bee pollen (http://www.webmd.com/balance/bee-pol...side-effects): You may also hear recommendations for using bee pollen for alcoholism, asthma, allergies, health maintenance, or stomach problems, but there is no proof that it helps with these conditions. Before you take any natural product for a health condition, check with your doctor. Bee pollen is also recommended by some herbalists to enhance athletic performance, reduce side effects of chemotherapy, and improve allergies and asthma. At this point, medical research has not shown that bee pollen is effective for any of these health concerns. Until Dr. Dodds publishes her results on saliva testing in a reputable refereed journal--and even then, the results will have to be replicated by others--I cannot take her recommendations seriously. | |
04-09-2015, 07:01 AM | #66 | |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
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Thank you so much for your feedback on all of this! I don't have the patience or the expertise to do all of this.
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04-09-2015, 07:38 AM | #67 | |
T. Bumpkins & Co. Donating YT Member Join Date: Dec 2008 Location: New England
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I'm glad you brought up the book because I actually paid $9.99 for the kindle version. I am not a vet, not a veterinary nutritionist, and don't even work in the veterinary industry but I DO interact with MANY veterinary specialists and have been getting sound dietary recommendations for my animals from a veterinary nutritionist for nearly 7 years now. As a lay person, though, I find that the book espouses unbalanced and impracticable diets for dogs and makes some really strange suggestions. For example, an apple should be fed to my senior dog with heart disease....really??? How come his boarded vet cardiologist hasn't mentioned the curative apples? Before someone comes along and says the cardiologist is invested in "drugs" and "money" please know that this particular hospital is a CHARITABLE HOSPITAL, a nonprofit, with veterinarians earning far less than they could get in the private sector. I'm quite sure if they thought an apple could help my 15 year old dog's genetic mitral valve disease and subsequent remodeled heart, they'd buy me a bag of granny smiths!!! I have a problem also with some of the suggestions about epileptic dogs. Since I happen to have an epileptic yorkie who is under the care of three board certified specialists (neurology, internal medicine, nutrition), I have to laugh at the items in the book -- 1. Don't feed high glycemic carbohydrates. Teddy likes carbs and his recommendations are to eat white potato, pasta, white rice. He happens to eat peas instead, but those were his recommendations and all of those are high glycemic carbs. They do not trigger seizures!!! I should also add here that the dog has a BCS of 4.5/9 and is slightly too lean! TOO LEAN. Not FAT, not CHUBBY, not even a little love handle. 2. Don't feed beef. What is this woman saying now????? TEDDY LOVES BEEF. Haven't seen him fall over into a grand mal seizure from eating beef in the last 6.5 years of his life. 3. Teddy should eat plenty of gelatin. There is no citation to a source that is reputable, but rather, a citation to a lay person epileptic dog website. There is a recipe in here for dog gummies and I admit, I might try it because I can gel up some chicken broth that Teddy might like. 4. Vets don't know how to test for thyroid disease. What is this woman talking about!!! My vets know how to run thyroid tests!!!!!!!!!!! I feel I wasted $9.99. The only good thing that came out of this purchase (other than to feed the magic apples to cure my dog's heart and the special gummies for Teddy) is that a portion of the sale is donated to my favorite charity by Amazon.
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04-09-2015, 07:58 AM | #68 | |
Donating YT 10K Club Member Join Date: Aug 2007 Location: S. W. Suburbs of Chicago, IL
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__________________ “Never argue with a fool, onlookers may not be able to tell the difference.” Mark Twain | |
04-09-2015, 08:15 AM | #69 |
Donating YT 10K Club Member Join Date: Aug 2007 Location: S. W. Suburbs of Chicago, IL
Posts: 12,235
| Interesting that I found a human version on the NurtaScan.
__________________ “Never argue with a fool, onlookers may not be able to tell the difference.” Mark Twain |
04-09-2015, 08:29 AM | #70 |
YT 2000 Club Donating Member | Canadian College of Naturopathic Medicine | $3M research grant awarded to Canada-US researchers investigating the impact of naturopathic medicine on late stage cancer survival while human medicine at least some more research is being done.
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04-09-2015, 08:33 AM | #71 | |
YT 2000 Club Donating Member | Quote:
That is a piece of pure BS Bee pollen seems to be good for everything - when ever I read a claim like this I dismiss it! Why does she even go there! crap
__________________ Razzle and Dara. Our clan. RIP Karma Dec 24th 2004-July 14 2013 RIP Zoey Jun9 th 2008-May 12 2012. RIP Magic,Mar 26 2006July 1st 2018 | |
04-09-2015, 08:58 AM | #72 | |
Yorkie mom of 4 Donating YT Member Join Date: Feb 2008 Location: LaPlata, Md
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__________________ Taylor My babies Joey, Penny ,Ollie & Dixie Callie Mae, you will forever be in my heart! | |
04-09-2015, 09:00 AM | #73 |
YT 2000 Club Donating Member | For the thyroid this might be a part of the rationale: Development of Accurate Diagnostic Tests for Canine Hypothyroidism | AKC Canine Health Foundation Development of accurate tests Dr Jean Dodds I remember her saying years ago that when the T4 simple test is simply not good enough to rule out thyroid problems especially when repeat tests are at either end of the range - ie borderline low or high.\\
__________________ Razzle and Dara. Our clan. RIP Karma Dec 24th 2004-July 14 2013 RIP Zoey Jun9 th 2008-May 12 2012. RIP Magic,Mar 26 2006July 1st 2018 |
04-09-2015, 09:02 AM | #74 | |
YT 2000 Club Donating Member | Quote:
Going to go out and order that are you?
__________________ Razzle and Dara. Our clan. RIP Karma Dec 24th 2004-July 14 2013 RIP Zoey Jun9 th 2008-May 12 2012. RIP Magic,Mar 26 2006July 1st 2018 | |
04-09-2015, 09:13 AM | #75 |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
Posts: 3,648
| Just so people don't think I'm making this up, here is a screen shot from the portion of Dr. Dodds' book about bee pollen. Note that Dr. Dodds uses Mercola as a reference: |
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