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01-09-2018, 07:22 PM | #1 |
Yorkie Talker Join Date: Dec 2009 Location: North Carolina
Posts: 22
| Protein Lessing Nephraphy I have a Yorkie who I was going to get spayed.She is 9 yrs old.Got blood work done and urine tested.Urine test came back she had protein in her urine.Vet said she has Protein Lessing Nephraphy.What could cause this and what is the outcome?All this came as a shock to me.The vet also said she has 2 little bumps on her mammary glands.So spay is on hold.Has anyone ever had this with there Yorkie? |
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01-10-2018, 05:06 AM | #2 | |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
Posts: 3,648
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Since it's a serious condition, you should definitely get a second opinion just to be sure of the diagnosis, or get a referral to a board-certified veterinary specialist in kidney diseases. | |
01-10-2018, 08:04 AM | #3 |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
Posts: 27,458
| Yes, I have had 3 pups with this. One is currently living. You cannot diagnose a pup with PLN based on one urine test. Did the blood work show a lowered albumin? I am assuming it may have...or the vet would not have diagnosed this as protein can be in the urine for other reasons. Did they do a UPC? (urine protein creatinine ratio) I would definitely hold off on surgery until all of this is clear. If you can, a consult with an internal med specialist might be helpful, but isn't totally necessary. Your vet should know how to treat this. With the first pup who was diagnosed with PLN I was told she had probably at most one year to live. She went on to live for 4 1/2 years. Here is a link to her story: http://www.yorkietalk.com/forums/sic...phropathy.html
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01-11-2018, 09:37 AM | #4 |
Senior Yorkie Talker Join Date: Sep 2006 Location: Sylvester. Georgia
Posts: 92
| Years ago I had an older female with PLE, Protien Loosing Enteropathy. Does anyone know if PLN is the same? |
01-11-2018, 09:56 AM | #5 |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
Posts: 3,648
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01-12-2018, 03:48 AM | #6 |
Furbutts = LOVE Donating Member Moderator | This is probably my very favorite article on PLN, but it's very techy: VetFolio. PLN is always caused by something *else* -- you need to find the underlying CAUSE! That is the vet's next step, unless they already know the underlying cause...?
__________________ ~ A friend told me I was delusional. I nearly fell off my unicorn. ~ °¨¨¨°ºOº°¨¨¨° Ann | Pfeiffer | Marcel Verdel Purcell | Wylie | Artie °¨¨¨°ºOº°¨¨¨° |
01-12-2018, 05:35 AM | #7 | |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
Posts: 27,458
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With the OP's dog, I spoke with her the other day and they are doing further testing to definitively diagnose this. If PLN is found early, it can be treated successfully is what I have found. Most of what I read in the beginning and what the specialist told me was life expectancy was about one year. Scared the heck out of me. In both Olivia and Rookie and in 107Barney's pup, Daisy, it was found during routine blood and urine testing....before symptoms were showing up. All three lived way beyond one year after diagnosis!! Rookie is still here with me. This is why I harp about yearly vet exams and lab testing.
__________________ Last edited by ladyjane; 01-12-2018 at 05:37 AM. | |
01-19-2018, 10:14 AM | #8 |
Furbutts = LOVE Donating Member Moderator | Linda - sometimes it can be genetic, but I think that's more breed specific. In most cases, PLN is caused by an underlying disease. In my foster Tucker's case, his PLN was either caused by his Erlichia or his pancreatitis - we can't be sure which . The key to best prognosis is early diagnosis of PLN and identifying underlying cause and treating it in time. And from that article - some other causes: Diseases associated with glomerulonephritis in the dog include infectious diseases (heartworm disease, Ehrlichiosis, Lyme disease, Rocky Mountain Spotted Fever [RMSF], pyometra, chronic bacterial infections, bacterial endocarditis, septicemia, Brucellosis, Leishmaniasis, Trypanosoma, and infectious canine hepatitis), neoplasia, inflammatory diseases (pancreatitis, systemic lupus erythematosus [SLE], polyarthritis, chronic skin disease, and prostatitis), and other conditions (Cushing's disease, diabetes mellitus). In cats, GN can be associated with feline leukemia virus, feline infectious peritonitis, mycoplasmal polyarthritis, neoplasia, pancreatitis, SLE, other immune diseases, and diabetes mellitus. In many cases, an underlying cause cannot be discovered, and these are classified as idiopathic. Amyloidosis can be a familial disorder in Shar Pei dogs and Abbysinian cats, and it can also occur in conjunction with chronic antigenic stimulation (i.e. chronic pyoderma, neoplasia). Breeds with a high incidence of familial glomerulopathy include Soft-coated Wheaton Terriers and English cocker spaniels. Familial PLN has been reported in many other breeds.
__________________ ~ A friend told me I was delusional. I nearly fell off my unicorn. ~ °¨¨¨°ºOº°¨¨¨° Ann | Pfeiffer | Marcel Verdel Purcell | Wylie | Artie °¨¨¨°ºOº°¨¨¨° |
01-19-2018, 11:40 AM | #9 | |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
Posts: 27,458
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I am not disputing the other issues/causes.
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01-19-2018, 11:45 AM | #10 |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
Posts: 27,458
| Oh, but yeah, let me add that I would not expect my vet to just assume it was genetic. Both of mine had full workups. I just have a strong feeling that it is becoming more of a genetic issue in yorkies due to breeding...of course that is not based on anything but MY thoughts and the fact the vets see a lot in yorkies.
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01-22-2018, 07:07 AM | #11 | |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
Posts: 3,648
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This test is currently available only for those two breeds, but I'll ask the primary researcher on the project if they have studied other terriers such as Yorkies and let you know what I find out... | |
01-22-2018, 02:24 PM | #12 | |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
Posts: 3,648
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01-22-2018, 04:13 PM | #13 | |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
Posts: 27,458
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01-24-2018, 06:00 AM | #14 | |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
Posts: 3,648
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Last edited by pstinard; 01-24-2018 at 06:02 AM. | |
01-24-2018, 06:28 AM | #15 | |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
Posts: 27,458
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ple; lymphangectasia, pln; nephropathy |
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