| pstinard | 04-22-2015 06:00 AM |
Quote:
Originally Posted by pstinard
(Post 4552736)
Yay!!! A question I can answer!!! From Systemic review on drug related hospital admissions ? A pubmed based search : Abstract Background
Drug related admissions have significantly increased over the past few decades. According to various studies on drug related hospital admissions, it was estimated that around 5–10% of hospital admissions were due to drug related problems (DRP), in which 50% of them are avoidable. Objective
The objective of the study was to derive results from various studies conducted on drug related hospital admissions and have an overall view about the incidence, frequency, cost of treatment, major causative drugs, problems for drug related hospital admissions, and preventable drug related admissions and summarize the factors responsible for the occurrence of DRP. Method
Relevant literatures related to ‘drug related hospital admissions’ were obtained from PubMed database. Articles that were published from October 2007 to September 2012 were collected. All the studies being shown in the search results were considered for the study irrespective of the specialty department. Results
A total of 366 articles were found based on the keyword ‘drug related hospital admission’, ‘drug related problem admission’, and ‘adverse drug event admissions’ search. Out of which 49 articles were identified to be showing relevance to the study. Non-English, abstract-only articles, and out-patient adverse drug reaction (ADR) studies were filtered from 49 articles. Finally 15 articles were taken up for the study. Systemic analysis was made on these articles and the results were summarized. Conclusion
Most of DRP studies were retrospective, multicenter studies conducted in general populations in Europe. The main objective of the studies was to estimate DRP frequency, incidence, risk factors and trends of DRP hospital admissions. Anti-neoplastic agents, CVS drugs and CNS drugs were related to most of the drug related problems. These studies concluded polypharmacy and older age were the major risk factors for developing drug related problems. It was found that the cost for the management of DRP was directly proportional to severity.
| Here's some info copy and pasted from this article about what kinds of drugs we're taking about :
One-third of the studies reported that antineoplastic agents ( Brvar et al., 2009, Carrasco-Garrido et al., 2010, Menéndez-Conde et al., 2011, Posthumus et al., 2012 and Rodenburg et al., 2011) as the major contributing drugs causing secondary infection, agranulocytosis, poisoning and constipation (Table 3). Same number of studies showed similar results by CNS drugs ( Hartholt et al., 2010, Posthumus et al., 2012, Rodenburg et al., 2011, Shamliyan, 2010 and Wu et al., 2012). Seven studies indicated that cardiovascular drugs ( Brvar et al., 2009, Conforti et al., 2012, Davies et al., 2010, Hartholt et al., 2010, Rodenburg et al., 2011, Singh et al., 2011 and Wu et al., 2010) as the major contributing class in which two studies showed diuretics ( Conforti et al., 2012 and Davies et al., 2010) as the major contributing drugs causing problems such as electrolyte imbalance. Antidiabetic drugs ( Brvar et al., 2009, Singh et al., 2011 and Shamliyan, 2010), immunosuppressive drugs ( Carrasco-Garrido et al., 2010, Posthumus et al., 2012 and Rodenburg et al., 2011) antibiotics ( Posthumus et al., 2012, Rodenburg et al., 2011 and Carrasco-Garrido et al., 2010) and anticoagulants ( Carrasco-Garrido et al., 2010, Rodenburg et al., 2011 and Shamliyan, 2010) were found as the major causal drug in 20% of the studies causing problems like hypoglycemia, osteoporosis, GI bleed, gastroenteritis and hemorrhage. Two studies each suggested that systemic agents and analgesics as the major drugs causing GI bleed and nephropathy. ( Hartholt et al., 2010 and Wu et al., 2010) One study implied warfarin ( Brvar et al., 2009) and aniplatelets ( Davies et al., 2010) as major contributing drugs causing complications such as bleeding. |
