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-   Sick & Injured / Emergencies Talk (https://www.yorkietalk.com/forums/sick-injured-emergencies-talk/)
-   -   Encephalitis (https://www.yorkietalk.com/forums/sick-injured-emergencies-talk/287723-encephalitis.html)

Lil Sis 07-07-2016 08:09 AM
Quote:
Originally Posted by CherubRock (Post 4638117)
What symptoms did your dogs display with this? Because the vet thinks theres a slight possibility Dave has encephalitis or meningitis.
for Remy it was her sight-- blank look, walking in circles, head tilt, loss of control of hind legs.

Shicks 07-08-2016 04:26 PM
So very happy, happy your Sissy is doing well. Puppy prayers for more improvements. Wish my Titan could have went to 1/4 of a pill a day. With his GME it was many meds every day. The end result was the same. I feel so sad for any pup & parent dealing with this.

mikajo 07-21-2016 09:51 AM
We are now down to 1/4 a pill, every other day.. only been a week..but still trucking along.. She still has the slight sluggishness in her hind legs. She goes in next week for a check up and some blood work.

mikajo 07-21-2016 09:53 AM
1 Attachment(s)
Quote:
Originally Posted by mikajo (Post 4649552)
We are now down to 1/4 a pill, every other day.. only been a week..but still trucking along.. She still has the slight sluggishness in her hind legs. She goes in next week for a check up and some blood work.
Sissy trying to lick her brother Chumlee :) Sissy never was a very playful girl,so when I catch her being silly, I love it!!

Maximo 07-21-2016 11:10 AM
Quote:
Originally Posted by mikajo (Post 4649553)
Sissy trying to lick her brother Chumlee :) Sissy never was a very playful girl,so when I catch her being silly, I love it!!
Adorable!! Wishing you continued good news.

Save

mikajo 07-21-2016 01:25 PM
Quote:
Originally Posted by Shicks (Post 4646357)
So very happy, happy your Sissy is doing well. Puppy prayers for more improvements. Wish my Titan could have went to 1/4 of a pill a day. With his GME it was many meds every day. The end result was the same. I feel so sad for any pup & parent dealing with this.
If you don't mind me asking..What all meds was he on? I am still so nervous every time we reduce her dosage, scared of a relapse :(

Layla04 03-01-2018 07:13 AM
I lost my Layla to NME in 2014. I also have read about vaccinations causing this. The smaller dogs presented with this first & now it seems all breeds are getting it. There is a great site called "New GME dogs" that will guide anyone who has to deal with this dreaded disease. I just adopted a new Yorkie puppy last year and have to give her the rabies this coming Monday. I am sooo paranoid about everything now. Anesthesia, flea and tick preventative, heartworm, etc. Anything that may effect their nervous system.

pstinard 03-01-2018 08:17 AM
Quote:
Originally Posted by Layla04 (Post 4754915)
I lost my Layla to NME in 2014. I also have read about vaccinations causing this. The smaller dogs presented with this first & now it seems all breeds are getting it. There is a great site called "New GME dogs" that will guide anyone who has to deal with this dreaded disease. I just adopted a new Yorkie puppy last year and have to give her the rabies this coming Monday. I am sooo paranoid about everything now. Anesthesia, flea and tick preventative, heartworm, etc. Anything that may effect their nervous system.
They don't really know what causes it yet. If I can find any more specific information, I'll post it. Here are a couple of general articles about NME:

https://wagwalking.com/condition/nec...goencephalitis

https://www.petmd.com/dog/conditions...breed_specific

pstinard 03-01-2018 08:29 AM
Quote:
Originally Posted by pstinard (Post 4754917)
They don't really know what causes it yet. If I can find any more specific information, I'll post it. Here are a couple of general articles about NME:

https://wagwalking.com/condition/nec...goencephalitis

https://www.petmd.com/dog/conditions...breed_specific
Here's a link to a 2008 article that studied the causes of NME in pugs: http://onlinelibrary.wiley.com/doi/1...08.0137.x/full. I'm sure it's behind a paywall, so I'll quote the relevant parts:

Quote:
Vaccination status was examined in NME and non-NME groups, because antigen exposure has been speculated to play a role in the development of various encephalitides, including NME.1,2,16 The proportion of dogs vaccinated within 1 month of disease onset and the duration between vaccination and onset were not significantly different between groups. Furthermore, only a small proportion of NME dogs (0.11) were vaccinated within 1 month of onset. Pugs with NME and a history of parvovirus vaccination had a higher death rate (hazard ratio = 2.35; Table 4), but this result was not significant (P= .053). If parvovirus vaccination is involved in the pathogenesis of NME, mechanisms are most likely immune mediated because dogs in this report had no identifiable parvovirus in brain tissue as assessed by PCR. In humans, vaccination has been associated with various immune-mediated encephalopathies.42–44 Measles virus vaccine, for example, has been speculated to predispose individuals to MS, whereas mumps vaccine has been associated with a form of postvaccinal aseptic meningitis.42,43 Despite these associations, the risk of autoimmune encephalitis after vaccination is believed to be exceedingly low in humans, in some cases on the order of 1 case per 1,000,000 vaccinations.42 The lack of clear association between vaccination and NME in this report is therefore not unexpected, especially considering the small sample size.
Quote:
Based on our data, NME appears to be a common cause of intracranial signs in Pugs. Pugs with NME seem to be predominantly young adult, female dogs. Although NME lesions were most common in the prosencephalon (60/60 dogs) as has been previously reported,1 a high proportion of Pugs also had involvement of the brainstem (24/59) and cerebellum (23/58). There was no obvious seasonal or geographic distribution, although most cases identified were from the western, midwestern, and southeastern regions of the United States. There was no apparent relationship between vaccination and NME, although data concerning hazard ratio and parvovirus vaccination suggest the need for additional investigations. CSF analysis typically identifies a lymphocytic pleocytosis (mean WBC count 120 cells/μL; range, 0–540). Mean survival time in this population of necropsy-confirmed cases was 93 days.
No significant association between vaccination and development of NME in that study, but they agree that larger studies should be done.

Shicks 03-01-2018 09:49 AM
So very sorry for your lose and this terrible disease. I know very well what GME is and does.
Lost my 7 year old Yorkie Titan from this heat breaking disease. He was diagnosed at age 5. For almost 2 years we spent 1,000's upon 1'000's of dollars to help him have somewhat a normal life.
University of Tennessee Vet. Hospital was very helpful.
He died just one week into his 7th birthday, Valentine's Day.
Worse day of my life.
Now we have Ruger, which has turned 3 years old. I'm on pins & needles constantly.
He has all the core vaccinations and 1 rabies so far. Before my Vet wants to re vaccinate I'm for sure going to have him titer 1st.
I refuse to give him more if he is protected.
I pray no one has to go through this very hateful disease with their baby.

Layla04 03-01-2018 12:00 PM
I am sorry for your loss. It is truly heartbreaking to watch your baby go through that. Felt so helpless. Our neurologist suggested we let her go since the progression of NME is so terrible. I have learned a lot more about it now. I still question our decision everyday even though I really don't think the suggested treatment would have bought us much time with her. And I don't know what quality of life any of us would have had. Her diagnosis was idiopathic. So they really don't know for sure what causes it. Seems like there is so much going on with our pets now. More cancer etc. I hope your baby has a long healthy life.

Layla04 03-01-2018 12:11 PM
Thank you for your response & for the articles. You are right they still don't know what causes it. Layla's diagnosis was idiopathic NME. But I will always question why & if I can do anything to protect my new pup I will do so. I will be titer testing for all the other immunizations but they force rabies every three years. I had my first yorkie (Chloe) for 17 years without any problems until the end. She died of renal failure. I never even had her spayed, I just watched her well & she really was not around other dogs. I did take her to the vet but never treated for ticks, fleas etc. So who knows. But the less chemicals the better.

Rachael1983 03-01-2018 12:52 PM
My Troy passed away from GME Granulomatous meningoencephalomyelitis very similar to what you're dog went through as well. Troy was 4 years old when I put him to sleep after a few weeks of watching him decline and hoping he would get better. I know how hard that was.

It is said and some research has been done that some neurological disorders in small dogs such as GME has been triggered by combination vaccines. Troy did have a combo vaccine not long before he started showing symptoms of the disease and I think that has had a lot to do with it in his case. I'm careful of this now with my current yorkie Emma.

Lovetodream88 03-01-2018 01:26 PM
Quote:
Originally Posted by Layla04 (Post 4754937)
Thank you for your response & for the articles. You are right they still don't know what causes it. Layla's diagnosis was idiopathic NME. But I will always question why & if I can do anything to protect my new pup I will do so. I will be titer testing for all the other immunizations but they force rabies every three years. I had my first yorkie (Chloe) for 17 years without any problems until the end. She died of renal failure. I never even had her spayed, I just watched her well & she really was not around other dogs. I did take her to the vet but never treated for ticks, fleas etc. So who knows. But the less chemicals the better.
Not spaying a dog is not just about watching them around other dogs there is an increased risk of mammary cancer for every heat they got through and then as they get older there is a huge chance they can get poymentra which will kill them and even if you get the emergency spay when they get it I have seen many many dogs still die within a few weeks. Anesthesia is VERY safe. Titer tests are also not reliable at this time much more research is needing to be done. I hope you give heart worm prevention at least because if your dog gets heart worms the treatment can kill them and if it doesn't it will leave them with lasting heart issues. I get sometimes it can be scary but really there isn't anything proving vaccines, heart worm prevention and so on cause any bad health issues.

mikajo 03-03-2018 04:36 PM
My Sissy girl passed away at the end of January...She fought this ugly disease for 2 yrs...She was having a relapse, so we took her to the vet..He gave her a big dose of steroids and something to help her rest..She had went all week barely sleeping..We didn't get 3 blocks down the road and she died in my arms...I am pretty sure it was just to much for her ,already strained heart and lungs..I am at peace knowing I was there with her and she is no longer suffering..It was almost a year to the day that we lost our little Taz..He was a 4lb yorkie and he fell off the arm of our recliner and instantly died of a broken neck..No matter how much we love and protect them,we just can't stop it all :(


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