Genetic testing for diseases in Yorkies still in its infancy... Hi, While doing research on available DNA tests for genetic diseases in Yorkies, I came across a peer-reviewed article from April 2013 that provides a link to an updated list of DNA tests available for genetic diseases in dogs and cats. Yorkies clock in with only three tests--two for eye problems (Primary Lens Luxation and Progressive Retinal Atrophy, prcd), and one for a metabolic disease (L2-Hydroxyglutaric Aciduria). Genetic testing for Yorkies is still in its infancy :(. Links to the labs that do the testing are provided: Canine and Feline Hereditary Disease (DNA) Testing Laboratories |
Oh, by the way, there are labs that do testing for coat color genes in Yorkies, including the Biewer trait, but since those are not diseases, they are not included in the database I linked to above. Oh, and there are also labs that do breed purity testing AND parentage testing. In other words, our dear little Minnie and her parents could be tested to she if she was the offspring of the two reported parents--however, the cost is triple that of a single dog DNA test, so it gets kind of expensive. I only recommend the breed purity test for Minnie for now... Here's a lab that does coat color and DNA parentage testing for Yorkies: http://www.healthgene.com/canine-dna-testing/ |
You are such a breath of fresh air on YT. I have a feeling you have some connection with U of I vet school????? Thank you for everything you have contributed in the short amount of time you have been on this forum. |
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I knew that they were working on a test that would tell you if your dog had the parti trait, but as of last year it still hadn't been available. I assume this is the same test, maybe one of our breeders here knows. Anyway, this should take lots of the guesswork out of things and alleviate some of that paranoia. A question for you pstinard, I've read that they can produce the genetic code for cats, but they can't do this for dogs yet because the code is so rich and diverse. Is this true and am I even phrasing this correctly? It had something to do with cloning a dog vs. cloning a cat. |
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It looks like the DNA of a boxer has been sequenced too. Here is a link to information: Dog Genome Project | Broad Institute of MIT and Harvard It looks like the dog genome was sequenced two years before the cat... |
Your contributions to date, and I am sure in the future, are absolutely priceless...especially to those of us that are breeding these wonderful dogs, and trying so very diligently to step gingerly thru the minefield of diseases and conditions that affect our beloved breed! |
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Oh this is interesting for any dog, not just the Yorkie: Dog Diseases | Broad Institute of MIT and Harvard We need DNA samples from purebred dogs suffering from the diseases we are currently studying (described below), as well as from older, healthy dogs from the same breeds. If you would like to submit a sample, please ask your veterinarian to collect 5 milliliters of blood from your dog (click here for more information). Although we appreciate that many people and dogs want to help, using samples from only purebred dogs will ensure the fastest progress for all dogs. Diseases we study: Cancers •Hemangiosarcoma • Osteosarcoma (bone cancer) • Lymphoma • Mast Cell Tumors (MCT) • Mammary Tumors • Melanoma (skin cancer) • Glioma Cardiovascular Diseases •Dilated Cardiomyopathy (DCM) • Degenerative valve disease Neurological Disease & Behavior •Degenerative Myelopathy (DM) • Idiopatic epilepsy •Obsessive-compulsive disorder (OCD) Immunological & Metabolic Diseases •Familial Shar-Pei Fever (FSF) • Addison's disease •Symmetrical Lupoid Onychodystrophy (SLO) •Atopic dermatitis •Diabetes •Lymphocytic thyroiditis •Exocrine Pancreatic Insufficiency (EPI) •Toller Diseases (SLE & SRMA) Other •Dermoid sinus (DS) •Juvenile Demodicosis •Juvenile Renal Dysplasia (JRD) •Hairlessness/Canine Ectodermal Dysplaysia (CED) •Progressive Cone-Rod Dystrophy (PCRD) •Progressive Retinal Atrophy (PRA) • Pseudopelade •White coat color •Pyometra |
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Cancer. Cataracts Deafness - some tests are available genetically for some breeds. Heart Disease of various types how about PDA which can affect almost any breed? DLSS thought to be genetic in a few breeds no genetic marker yet. Hyperuricosuria genetic test of of U of Davis. is that the same as the L2 genetic test? You have stepped into a vast pool. We the dog fancy world and vets are literally in the infancy of having many true genetic tests. I can not stress enough how important this is. In particular those genetic markers and tests that pre screen across very many breeds of dogs. You are a Godsend to this board if you can bear with us breeders, who have so many questions. I am looking at COI and how to interpolate sibling results into a breeding matrix selection program? And as we all know we hardly ever get sibling results. |
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