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That, Izzy, goes back to the politics.. the testing and the lab are not part of politics. We need to know, be it mutt or purebred what we, as a whole, can do to improve the quality of these dogs and if there is a test that is not known, then please share it... Put a bunch of puppies in a roomfull of toys and they will all play together... they get along, it is the owners who do not... and, at this point, who cares? Let us test our puppies and dogs with this new test, send it to this lab and have a better understanding of what can go wrong in any breed... I do not think that is asking too much of any person.... Donna |
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If you want to test your dogs it is very easy. Email BTRA and order a swab kit. By the way, how many members have ordered the JRD tests that I told your club about? |
I take the problems with puppy mills very seriously, and I think it's wrong of you to suggest that just because someone is in another club, they are in a puppy mill registry. I don't think you should throw the word around lightly, and many of us are really concerned about the breeding conditions of puppy mills. This isn't about prestige or saying my dog is from xyz registry, it's about extreme abuse of dogs. |
I agree wholeheartedly Donna1134!!! It is about the dogs. :) |
Biewer Testing I prsonally think Biewers are adorable. I love their coloring. I thought they were Yorkies bred by German breeders trying to achieve a variation in color. I thought they were still Yorkies. Do Biewers have more potential health problems than refular Yorkies? My goodness! With our American Yorkies, we have to deal with AAI, Liver Shunt, Laxating Patella, Colapsed Trachea, etc. I bought Tucker from a good breeder, but he had AAI. The breeder had never had the problem before. His brother and sister were fine. I don't understand all the fuss about Biewers, Iguess I'm just uninformed. Tucker's Mom |
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I own Biewers and love everyone of them, I don't think they have anymore health problems than any other breed. all of mine seem to be very healthy and have been tested for Ls & Lp except 1 he will be when he is 1 yr old |
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The lab has tested “at least” 25 dogs for each of the markers they claim cause disease in specific breeds. (Note that in doing similar testing on humans, pharmaceutical labs do the tests thousands of times.) 25 dogs is less than that required for minimal statistical analysis by at least 17%. As a result, their statistics cannot be relied upon for decision making. In other words, their error rates are far too high for any useful conclusions regarding any specific dog to be made. The DNA studies completed so far, and there have been surprisingly few of them are looking for “markers” only. A marker is not what most people think it is. The canine genome consists of 2.4 billion “letters” (each letter is the “name” of a particular protein). A marker is only an indicator that a specific sequence of letters, within one of the dog’s 39 chromosomes is correlated with a particular trait. For example consider this: I am going to buy a used car. I know that the used car has 75,000 miles on it, and I can see that it is highly polished and has good tires. I cannot see the inner workings of the engine or the transmission. However, I can take it for a compression test. The compression test will let me know the health of the engines cylinders and its valves. So, I have the compression test done and discover that one of the cylinders has a different reading from the others. From this information I determine that the engine MIGHT need some costly repairs in the near future. However, what I did realize was that the compression test was given to a car that uses various numbers of cylinders, depending on the work load asked of the engine (yes, there are cars like this—Honda calls it i-VTEC—it saves lots of gas. The compression test is nothing but a marker. Depending on the car it is used on, the testing methods, and other factors, it may give information useful to the used car buyer. However, in this example, it gave the used car buyer information that led to an incorrect conclusion. Ok, using this same idea for dogs—If I have a great Dane, and I research its DNA for longevity characteristics, I may come to the conclusion that a specific “marker” is present for great Danes that live longer than others. This marker may not be the cause of long lives, it may merely be present for a majority of dogs that live a long time. Since longevity is not caused by a single gene—that is, it is caused by the relationships of many genes (term: “polygenetic”)—the marker does not tell the whole story. It is merely the indicator that “long life genes” may be present. If you then look for this gene in a completely different breed, say a Maltese, I might find it. Does that mean that the Maltese with the marker present will live longer? Answer: No. Remember: longevity is based on many genes working together in a specific fashion, and that the marker we found in our original research was based on great Danes. To utilize the marker in Maltese means that we need to test a bunch of Maltese dogs and cross compare the results. Since doing this takes time, and costs money, the results are slow in coming. All that is fine and good, but what does it tell us about using a DNA test as an indicator of probability of disease in the future, for a beagle, if the test was developed on a schnauzer? Answer: Nothing. A test developed on one breed is largely useless for other breeds unless it can be statistically validated. The company has not statistically validated their tests for any breeds except the ones that they claim. So, the tests that are being conducted on the Biewers are completely bogus. They cannot be used to ascertain the probability of any specific dog becoming ill. As a matter of interest, the tests should not be used on the breeds for which they have been validated. This is because they only tested 25 dogs of each breed. They need to test at least 900 dogs (that would give them 30 groups of 30 dogs each….enough for a valid statistical and very meaningful study.) |
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As you explained it, then having all the tests on a particular Breed Specific Club gives the unsuspecting public with a false sense of security. |
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Ihope it's just a sales pitch, because then, those breedere--from that club would KNOW that they are telling lies. What really scares me is when people are so ill-informed that they don't even know that they are telling lies. It is this type of person that is truly dangerous. That does not mean that telling lies is ok--I just think it is better to be a liar and know that you're a liar, than to be stupid. |
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And I want to thank all of those interested persons who kept this important thread alive and kept it on the subject!!! |
I think this is a very important topic. Gee litter mates are called two different things: Biewers or Biewer Terriers....depending on who is selling puppies. I don't think the Mars Test is accurate. I met several animal genetists on the K-9 cruise all of whom were in agreement that the Mars test was not developed to distinguish a new breed much less determine purebreeds. |
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The DNA testing for disease is even less accurate. It is even less accurate than "less accurate" if it is used for dogs that are not in the primary groups. Tests developed for weimaraners (spelling) are not valid for beagles etc. Anyone who relies on the MARS test to prove that their dog is unique, a new breed, or anything else, is blowing smoke. They simply do not have a clue what they are talking about (or they are liars.) Similarly anyone who relies on DNA for disease testing to prove that their dog is healthy or their breeding lines are healthy is blowing smoke--albeit of a different variety. These people also do not have a clue what they are talking about (or they are liars.) The facts about DNA are stunning: as scientists we actually know far less about DNA than the general public thinks we do. The only organism for which we really understand the DNA is the pea--the garden pea--the one you eat at dinner. We understand the pea very well. The rest we do not understand. Sure, we have mapped the genome. That tells us where specific proteins are found. We know what a very few of those do. We do not know how they work together. Our knowledge of human DNA is VERY limited. ...and we have lots of money to research human DNA. Our knowledge of dog DNA is even more limited--there is very little research money available for dog DNA. Anyone who claims that they understand dog DNA is either a fool or a liar. |
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The big question....are those people bright enough to know they are stupid??? :confused: |
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I think not. |
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Yeah, especially when their leader posts that she holds a doctorate degree when she has no education after junior college--in an apparent fraudulent attempt to get people or companies to provide her with special considerations. --Just left the RAW out of PhD....P H D ++ R A W = PHRAWD |
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I am shocked at the responses of some of you old time breeders. You are agreeing with statements made by newbies as though they are speaking the gospel truth. What an embarrassment to the creditability of older, more experienced breeders. Has anyone researched these statements to see what are fact and what are fiction? Looks to me like someone's feeling got hurt, so they are lashing out like little school kids, calling names. Where are the adults here? |
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I'm afraid you just don't have the history of dealing with some of those people in a business and personal sense. If you had that experience, you would be upset too. |
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The old time breeders are reputable breeders that understand marketing 101..Dr. |
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What are you talking about marketing 101 Dr? I know a lot of old time breeders and marketing is not their priority. Any reputable breeder would agree. Judy |
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Why is everyone arguing about the lack of knowledge and the vanity that people have --whice manifests in their being unable to be honest? |
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