An important article Linking Vaccines To Joint Disease In Dogs As a pleasant surprise this article actually references studies. The link between vaccines and collagen degradation is concerning. I will point out that in general what she says about the incident rate of HD is still high after 30 yrs or so of screening is accurate... go to offa and see some of the stats - What I believe to be incorrect is the generalized statement as fact that at 8wks old HD even moderate to severe is not radiographically present in puppies is not supported by any wide reaching broad based studies. The PENNHIP method is a relative newcomer on the block which uses a different diagnostic methodology and purports to accurately assess as early as 2-3 months if this dog will develop HD. Maybe she is using the stats from PennHip - I don't know What again is not fact or at least generally accepted is that nutritional deficiencies or insufficiencies and or environmental factors play a huge role. I know of one study a good one that suggests this (a European study) so of course in North America it does not get much attention. That self same study made sense to me. Control rate of weight as the puppy develops - keep on level non slip surfaces until 4mths of age or so etc. |
Interesting indeed. It seems so much can be linked to vaccines / overvaccinating, potentially. Goes to show us just how important it is to be the advocates for our dogs in preventing them from being overvaccinated by a vet who does not follow current/modern vaccine protocol (and many still don't, shockingly!). |
Hi Gail. The article misrepresents the "Purdue study" on antibodies formed to collagen. The antibodies were raised against fibronectin, and specifically, the heparin-binding domain of fibronectin, not the collagen-binding domain. And the Purdue study didn't simply "end" at 22 weeks. The beagles were killed at 22 weeks, and the researchers performed necropsies on the dogs and didn't find any significant differences between the vaccinated and unvaccinated dogs as far as pathologies go. Of course, 22 weeks may have been too early to conclude the study. And it looks like there were only five dogs in each group, a very small population. The Purdue study, which is not behind a paywall, can be found here: Purdue Vaccination Study Conclusion of the study: "In conclusion, we have demonstrated that vaccination of dogs using a routine protocol and commonly used vaccines, induces autoantibodies. The autoantibody response appears to be antigen driven, probably directed against bovine antigens that contaminate vaccines as a result of the cell culture process and/or as stabilizers. The pathogenic significance of these autoantibodies has not yet been determined." That's the only study that this article cites in full. If I get time this week, I'll try to find some of the other studies that they mention, but don't give citations for. I'm not saying that vaccination (or over-vaccination) doesn't lead to joint disorders. I just think that the information as presented in this article doesn't demonstrate that it does. |
Once more I type a response I don't know why this happens so much but I get 3/4 of the way done and whamooo my response disappears/ Good grief do these supposed docs know how to read an article - not to read from a biased or only seeing what they want to see, but from an objective viewpoint. On the 22 wks - offa will not certify hips or elbows clear of HD until 2yrs old. Presumably they have a solid rationale for this - so it is hard for me to see at the tender age of 22 wks that we are going to learn a whole lot. Pennhip asserts they can tell *if* a dog will develop HD or ED not that they have it. I posted another news article that we have found the gene for HD in GSD and Berners I believe and at Cornell Unive a genetic study is going on for my breed the BRT for HD gene. Finding the gene is a good beginning! But it still doesn't answer the important question of environmental factors and the impact they have. There is one European study that has looked at this - and found a co-relation of positive environmental factors create both less severe HD in the dog - and an overall lowered incident rates. The factors they found seemed to make intuitive sense to me or at the minimum were common sense if you think about it a bit. That study is posted here. I have posted elsewhere here for GSD and Berners the HD gene has been found! There is an ongoing BRT study to identify the HD gene in my breed. Hopefully we shall have some exciting news in the next year or two! |
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