Glow in the dark dog A cloned beagle named Ruppy – short for Ruby Puppy – is the world's first transgenic dog. She and four other beagles all produce a fluorescent protein that glows red under ultraviolet light. A team led by Byeong-Chun Lee of Seoul National University in South Korea created the dogs by cloning fibroblast cells that express a red fluorescent gene produced by sea anemones. Lee and stem cell researcher Woo Suk Hwang were part of a team that created the first cloned dog, Snuppy, in 2005. Much of Hwang's work on human cells turned out to be fraudulent, but Snuppy was not, an investigation later concluded. This new proof-of-principle experiment should open the door for transgenic dog models of human disease, says team member CheMyong Ko of the University of Kentucky in Lexington. "The next step for us is to generate a true disease model," he says. However, other researchers who study domestic dogs as stand-ins for human disease are less certain that transgenic dogs will become widespread in research. Dogs already serve as models for diseases such as narcolepsy, certain cancers and blindness. And a dog genome sequence has made the animals an even more useful model by quickening the search for disease-causing genes. Most dog genetics researchers limit their work to gene scans of DNA collected from hundreds of pet owners. More available here: Fluorescent puppy is world's first transgenic dog - life - 23 April 2009 - New Scientist |
So now instead of teacups, everyone will want a glow in the dark puppy? :p I'm all for science and research, but I think this is a bit much. What's the purpose of putting a sea anemone's genome into a dog? Is it just because you can? (general you, not directed at anyone) |
I'm scared.... |
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Now you're thinking! Rave Yorkies anyone??? |
awwwww yeeeeeeahhh, they are way ahead of me. Oh you know what else I just thought of. At raves, there are scavenger types. They go around with their phones using them as flashlights looking against the walls or whatever for dumb drunk or high people to forget their wallets or cell phones, and these parasites collect them. That's what I will use these dogs for next time I go to a rave. :D I will make a killing! That was a joke btw. |
Makes me queasy! |
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This was from FoxNews: South Korean scientists said on Wednesday they have created a glowing dog using a cloning technique that could help find cures for human diseases such as Alzheimer's and Parkinson's, Yonhap news agency reported. A research team from Seoul National University (SNU) said the genetically modified female beagle, named Tegon and born in 2009, has been found to glow fluorescent green under ultraviolet light if given a doxycycline antibiotic, the report said. The researchers, who completed a two-year test, said the ability to glow can be turned on or off by adding a drug to the dog's food. "The creation of Tegon opens new horizons since the gene injected to make the dog glow can be substituted with genes that trigger fatal human diseases," the news agency quoted lead researcher Byeong-Chun Lee as saying. He said the dog was created using the somatic cell nuclear transfer technology that the university team used to make the world's first cloned dog, Snuppy, in 2005. The scientist said that because there are 268 illnesses that humans and dogs have in common, creating dogs that artificially show such symptoms could aid treatment methods for diseases that afflict humans. The latest discovery published in Genesis, an international journal, took four years of research with roughly 3.2 billion won ($3 million) spent to make the dog and conduct the necessary verification tests, Yonhap said. Read more: Korean Scientists Produce Glow-in-the-Dark Dog - FoxNews.com |
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