Lexi,
Try shutting your bedroom door at night.  It will lessen the probability of her hearing noises in other parts of the house and keep her from running out of the room to bark at something that she might not have even seen or heard if the door was shut.  I shut my door at night bc I don't trust my boys with free run of my house, but I do think it helps to cut them off from the BIG OPEN HOUSE!  (your house is big to a small yorkie, no matter if you think its big or not) lots of things to feel threatened by in all that space in the dark when mommy is not paying attention!