This Lepto thing was buggin me. Here is a site that explains it.
http://www.canismajor.com/dog/lepto.html In another article it said dogs under 20lb have a better chance of getting a reaction from the shot. After reading the article my state (Texas) isn't one of the states that has a lot of reported cases. Hope this helps. I am going to talk to Doc about it before I give it to my dogs. I can go to bed now it's 1 am and I have learned alot from this site today