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Originally Posted by Yorkiemom1 Thank you Phil for taking the time to print this....it just blows my mind how all this is unfolding and advancing! |
Thanks! My takeaway from the article, in layman terms, is that in Maltese dogs, liver shunt is caused by mutation of a single gene, and the mutation is common. However, the mutation is not completely penetrant, which means that not every dog that carries two copies of the mutation will get the disease. That makes mapping and identifying the gene responsible more difficult, but not impossible, and they are still hopeful and working on it. They don't mention Yorkies in the article, but I'm hopeful that once they isolate the gene in Maltese, they will find that the same gene is affected in Yorkies with liver shunt as well.