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					Originally Posted by 107barney  Here is my advice.
 I would use the Frontline because there is a flea problem in NYC and also a tick problem, and the information you're googling about isn't what I would call scientific or reliable.  I've been using it for 14 years without a flea, tick, or side effect/problem.  I've been using it for almost 6 years on my epileptic dog as well....
 
 Sentinel or Heartgard are both fine.  I used interceptor for years (that's sentinel without the flea component) and it was discontinued.  I almost went to sentinel but because I still need a tick med, I switched to heartgard.  It is safe for small dogs.
 
 You could also use Revolution which is dosed by weight.  The holistic people tend to like that one a little more than the others (not sure of their rationale) but I think the better products are the Heartgard +/- Frontline.
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  I think the reason that some people like Revolution is because it contains only one active ingredient (
Selamectin - Wikipedia, the free encyclopedia) that fights heartworms, fleas, dog ticks, and internal parasites, whereas some of the other brands contain multiple active ingredients to accomplish the same thing.  Also, so far (fingers crossed), Revolution has had relatively few adverse reactions.