My furkids are fine with storms. Ry does have a similar reaction to car rides although it has gotten better. We used Ace for away. It wirked somewhat. Then we put him on Prozac because he is anxious all the time (chewing carpet, etc.). That seems to work just as well in the car but obv it is for ling term use.
If you use Ace it does need to be giving about an hour before. I would not hesitate assuming his organs are happy.
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