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Old 01-13-2006, 05:31 PM   #27
BamaFan121s
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Location: Alabama
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OK, got home and found my info. I really wish I had kept up with everything better, but I'll give you what I've got. These are the major mitochondrial disorders prevelant in canines:

* Epilepsy (myoclonic)-NOT to include seizures resulting from injury/trama or due to an axiety (ie, a dog that has seizures during thunder storms) was studied in great detail by the AKC Canine Health Foundation
* Certain types of Dermititis
* Demodex-lack of specific T-cell production used as an antibody that causes certain forms of mange due to exposure of microscopic mites found on MOST dogs
* Deafness (Mitochondrial Encephalomyopathy)-not every possible cause of deafness, just one very prevelant type...this type IS more common in smaller breed dogs

Also, when I was actually looking into this last spring/summer, The University of Cambridge was conducting research to determine what nervous disorders in dogs could be attributed to this--they suspect this will account for a large number. They had determined it could be a contributing factor in heart failure due to a condition where the canine heart doesn't fully function properly when the dog is excited or partaking in strenuous activity/play. I think (if I can read my own dang writing!) that it is more prevelant in large breed dogs.
I did write a few sites down:
http://www.geocities.com/welshealth/...ng%20Inherited
http://www.vin.com/VINDBPub/SearchPB...00/PR00323.htm
http://www.geocities.com/welshealth/.../CANINEEPI.htm (This one was released by AKC and the Canine Health Foundation.)
Also, when I was looking into it, I read (most) of a book written by Rommy Faversham, "Inbreeding to Superior Females." It was mainly about linebreeding, which I honestly was clueless to at the time, which is why I read it, but it went into alot of details about genetics as it relates here as well.

Hopefully this will make sense--it has been several hours since my other post!
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