Hi,I have twin 8 yr olds very active etc so I know what your saying... I actually chose the two pups who were bigger than their sister for this reason. I think the best solution is to have a crate where you can make her comfy with toys etc while your gone. put a lock on it and keep her there till you come back....she will be safe and there will be no anxiety and no "Im sorrys" when you come back