Pet Friendly is my first choice
, but, there are times when it's not an option...I've checked into hotels that are "exterior entry", where you don't have to go into a lobby or inside the hotel to get to your room, we've been ok.....
We would turn the TV "loud"
when we were gone and always put him in soft sided crate in case housekeeping or someone HAD to enter.....
Wish you luck