That is a very good question and a tough one. Bioavailability is very strange. Take Atopica. Brand name Atopica (a "gel-cap") has a certain level of bio-A. However, studies show that if you switch your dog to generic cyclosporine (a powder) - it has less bio-A, and some dogs symptoms will markedly increase.
Generic cyclo., of course, is more affordable. Anecdotally - I can confirm this experience just as of this week...so it's funny you asked this right now. I've had Marcel on Atopica for about a year now? But Wylie's compounding Pharmacy happens to make Generic Cyclo. - so I thought we'd try it for Marcel - we tried it for about 3 weeks now - and sure enough....Marcel is chewing his paws again. So, it will be back to Atopica.
So, that's an example of how bio-A is so different from med to med
. So...my long point is...lol...it's tough to say about each particular medication, in terms of "which form" bc it can be so different for each individual med. Cyclosporine, for example, can also be put in a suspension...but I would wonder if that's really the best form for its bio-A
. It also depends on *where* in the system the drug is supposed to be absorbed/broken down (ie, tummy, small intestine etc...).