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Little ones can be so touchy and so durable at the same time.
I have a litter 3 weeks with one runt she is only 9 ounces .
I had to get up every couple of hours clear the path for her to nurse I always put her on the back teats and wait till the milk let down and she got a good meal.
Now she is doing well and can fend for herself.

What antibiotics did your vet put the pup on ( Amoxi)? A Shot should take 24 hrs to start to work.
A light tapping of the chest or ribs sometimes will help break up any fliud they have in there. Only one finger is needed kinda like burping them. Very lightly

I use a heating pad also much better they can move away if to hot or move to get more heat.

keep her warm, tummy full and with momma , hope the pup starts to improve for you

I use nutri drops also they work great one drop 2 times a day.
You can only do your best sometimes it is enough and other times it is not.