In comparison to your Border Collie and Peekapoo?
Yes, it is quite different. Yes it is completely different in so many aspects. The risks and issues with Yorkies are very unique and specific to the breed, as is the case with any dog.
I find this whole thread a bit concerning. It seems as if you are missing the main point that several of the experienced breeders here are trying to convey to you. Hmmm, how to put this delicately.... I realize that you claim to be experienced and well researched, and I'm in no way trying to accuse you of being anything but truthful with those statements, but based on the comments and questions you have asked, it seems as if maybe several others have picked up on tell tale signs that you are not as prepared as you think you are or as you could/should be. Something that experiences breeders would be able to easily pick up on, no? Unfortunately, it also seems that you are set in your decision, convinced that you are as prepared as you need to be and I doubt that anyone here will sway you to consider otherwise. That being said, I sincerely hope that everything works out to suit the best interests of your female and I encourage you to always strive to keep that as your primary concern.