I would not do it even though I have six dogs as I feel it is very important that a vet see my dogs. If you are not experience and you are doing this to save a few bucks (and it will only be a few bucks) it is not worth it to not have a vet see your little ones.
Also your friend better be very educated on what shots to give (some shots will kill a Yorkie) and keep complete records or she could get in trouble...again not worth it to me unless I was breeding and I still think I would have the vet do it so I have a vet looking at my puppies.
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