Nope, never had any problems and have had 6 Yorkies, 1 Bassett, 3 Pekes, 1 Mutt on it. We do it year round too. If they ever miss doses, it's recommended that they be tested before starting treatment back up again, so I just keep them on it.
Last edited by BamaFan121s; 03-05-2009 at 07:29 AM.
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