I would try this as just like mosquitos cannot live in oil neither can mites so i would put all four paws in olive oil for say 5-10 minutes if you can and then give a bath afterwards and try that as all the meds are very strong for demodex and the pup gets them from the mama as all dogs have mites but if their immune system is low the mites take over thus causing the prob so boosting the immune system with a good diet will help alot |