My friends dog had Demodex. They did the anti's and meds and special baths. The Vet was doing skin scraps and it was looking good, so they stopped, but they found out that the mites were gone on her body but still on her feet. So back to the meds, and the Vet makes sure to do the skin scrapes on her feet. I think she goes back next week to get tested. I know you have to stick with it and it does take a while