Hi guys, I tryed to search for anwers on my own but it would take me into 2008

ok my question is... my sister is breeding her minpin for the first time.. she just started bleeding yesterday, so when does she go to the breeder ? is it the 2nd week ? what is the time frame? the male belongs to her friend and she dont know either, it will be the first time for both, they are both 2yrs old. thanks so much for your help

trying to talk her out of this not an option, already told her the about things ive learned here, they are both adults and want to do this, just hoping maybe i can help some.