The lactulose is important to give 3 times a day preferably after meals...The milk thistle you can give at any time. I like to give it in the mornings. The Vitamin E, you can give any time...Nutrical...How much are you giving?
You can crush the Pill form of the milk thistle or if it's a capsule, you can open the capsule and pour the powder on yogurt like I suggested.
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