I just did a TON of research on this vaccine bc we're traveling in July to Minnesota, where it is endemic.
The efficacy of the Lyme vaccine is really poor - and it is one of the vaccines with the most reactions. I couldn't really find a single reputable opinion-leader online who thought this vaccine was really worth it. The published papers and the AAHA don't recommend it.
I decided to go w/ Preventic after several recommendations and reveiws about the collar.
Check it out here:
http://www.allivet.com/Preventic-Tic...gs-p/25166.htm
and:
http://www.preventic.com/
What's nice about it is that the chemical isn't an insecticide. Rather, it is a neurotoxin to the tick.