I would not use a vaccine that contains lepto in it, the dhlpp sounds to me like it does, lepto is not recommended for small dogs. But now your talking about me, I'm sooo picky when it comes to vaccinating. I also dont allow the rabies shot to be administered at the same time they receive the dhpp. I wait at least 3wks or more to give the rabies seperately. Some dogs do well with all these shots at once but why risk it with the lil ones, JMO.
He will be uncomfortable for a day or two, if you see him with skin reddened and swollen, breathing difficulty etc call/go to vet. Hope he feels better soon!
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