I haven't... my Mom has to her Lhasa Apso and had no trouble, of course she's about 15 lbs. though. Well, one cc is the same as one mL. There are 5 mL in in a teaspoon and 15 mL in a tablespoon. So, you should have given him approximately 1 mL or 1/5 of a teaspoon, which you did. Make sure it was a teaspoon and not tablespoon though. I know in humans, if the dose is therapeutic, it will give a sedative effect... which would explain the dog seeming tired. If the dose is too much, then it will cause the opposite of sedation, which is excitement... which may be the fast breathing. The two things are contraindicating themselves! I'm not sure what to tell you. I would google dogs and benadryl to see what you could come up with. You could enter Yorkie/Yorkshire Terrier and benadryl, yorkie and heavy panting after benadryl... your dog should seem a little tired, but I would be worried about the rapid respiratory rates if they keep continuing.
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