I was doing some reading and came across this on Dr. Karen Tobias' website for The University of Tennessee.
The link is the website that I am reading & then I also put in what I just read.
http://www.livershunt.com/
~ Urinary Tract: As the liver fails to detoxify ammonia and uric acid — the byproducts of protein digestion — the substances must be excreted in the urine. The abnormally high concentration of ammonia encour*ages formation of mineral salts, which can crystalize into rough*~ surfaced calculi, or stones. These calculi obstruct and irritate the kidneys, bladder or urethra, making urination painful and difficult, sometimes resulting in blood in the urine. Some dogs develop recurrent urinary tract infections, as Ellie did. Dogs with PSS tend to drink large amounts of water and urinate a lot.