We moved back in December and it wasn't a big deal. I did restrict access to certain rooms for a while until they got the hang of where they were to go potty at and which door to go to get outside- basically gave a refresher course in the house-breaking rules.
I made sure they stayed either in the kitchen or with me for a few days, till they got the layout of the house down.
Really the biggest issue was that they kept waiting to go home. (bless their little hearts...

) They would hang out by the door when they knew someone was leaving and they moped around for about 2 weeks! I still remember what a big event it was for all of us when they FINALLY starting playing with their toys and acting normal again. I think they thought we were just visiting another house and that any day we would be going home.