I won't scream but you might when you see this list!
So.... let's see...
George & Gracy (Might be ove the younger folks heads)
Samantha & Darren
Jeanie & Major
Lois & Clark (Superman)
Ronald & Nancy (if you are Republican)
Bill & Hilary (if you are Democrat)
Homer & Marge or Bart & Lisa (when they have a baby she can be Maggie)
Roy & Dale (Singing Cowboy & Cowgal)
Harry & Sally (Movie with "When"
)
Tarzan & Jane
Her are some obvious ones:
Romeo & Juliette
Bonnie & Clyde
Fred & Ginger
Fred & Ethel
Lucy & Ricky (or Desi)
Mickey & Minnie
Donald & Daisy