I'm certainly no expert, but the one thing that I suggest is definitley get the pre-surgical bloodwork done. A friend of mine has a boxer and he was terribly allergic to the anesthetic. We had Biddy's blood tested before she was spayed & the tests came out negative, but at least I felt better sending her in for surgery. My friend's Boxer is fine now (although they still have not been able to neuter him), but I'm pretty sure our little Yorkies aren't quite as tough as a Boxer (as much as they like to think that they are!). Good luck