Quote:
Originally Posted by Wylie's Mom  So the c.perf alpha toxin gene was positive - but the add'l testing was negative, so I'm assuming they were satisfied with these results...? Did they talk to you about that particular part? All dogs do have c.perf in their systems (as do humans) - but it's when overgrowth or consumption of c.perf overgrowth is a problem that causes infection level.
Gosh, at this point, I think I probably would do and Endo and a biopsy.
Also though -- have you traveled anywhere with the dogs and/or have they been kenneled anywhere...? |
We have not traveled anywhere, however they did go on walks around the neighborhood. They are constantly sniffing every piece of grass and poop. I know there was a lot of geese poop around at some point in early spring. I thought they may have caught something from that. Here is the additional text from the diarrhea panel, the vet did not mention anything about it:
A POSITIVE CANINE DIARRHEA PANEL PCR result indicates that the nucleic
acid (DNA or RNA) of that organism(s) was detected in the fecal
sample. In a patient with clinical signs of diarrhea, this supports
infection. Vaccination with a modified live coronavirus and/or
distemper vaccine may result in positive results for these viruses for
up to a few weeks post-vaccination.
Clostridium perfringens toxin genes (CPA, CPE, CPnetE/F) positive PCR
results should be interpreted based on their quantitative levels.
Note that recent or concurrent antibiotic therapy against Clostridium
will lower the quantitative levels. In animals with CPA or CPE gene
copies >300 Thous/g feces or CPnetE/F gene copies > 20 Thous/g feces,
the toxin may be contributing to diarrhea. In animals where the
number of copies of the gene is below the cut-off, this toxin is
unlikely to be contributing to diarrhea. Higher levels (>1000 Thous/g
feces) of the CPnetE/F toxin gene are associated with an increased
risk of hemorrhagic gastroenteritis.
EDIT: Found this article as well
http://vetmed.tamu.edu/gilab/service...ns-enterotoxin