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Originally Posted by ladyjane  I won't allow those packs. The problem is that most ear meds do have that side effect. I had it happen years ago with one of my pups from Mometamax. The Gentamycin is what causes it. I don't like the fact that the pack stays in the ear for so long...seems to me it might be stronger?? I don't know...might be an over reaction. I do know my vet doesn't use it as a first line of treatment...it is saved for the dogs who are difficult to treat or who have really bad ears and keep getting infections.
A friend recently had it happen with her poodle with the BNT . She called me crying one morning and I told her to take him to the vet so they could flush the ear. She did and the vet was insisting this doesn't cause hearing loss because there is no Gentamycin in it.. She told him to take it out anyway. He did regain his hearing but it did take about 2 weeks. I thought someone on here also had it happen as Phil said but I cannot remember who it was. I think I read somewhere that the ketoconazole in the BNT can cause it.
Bottom line though, is there is no treatment for it. I do hope Daisy gets her hearing back.
I wish vets would advise people of the side effects....especially with the Mometamax...I just got lucky and figured it out on day three of treatment. He was acting strange and I said something to him and he didn't look at me...I then looked up Mometamax side effects and bang...there it was. I still use that med as it does work but I monitor their hearing closely. |
I looked up BNT, and it contains exactly the same ingredients as Oti-Pack E: enrofloxacin to treat bacterial infection, ketoconazole to help prevent fungal growth, and triamcinolone to reduce inflammation, in a lanolin base. Both BNT and Oti-Pack E are manufactured by compounding pharmacies, so they do not have the same type of regulation as products produced by a pharmaceutical company.
If you google BNT and Oti-Pack E, there are many stories of permanent deafness resulting from the use of these products. That could be because people only write about the bad things that happen as a result of using a medicine, but still, the numbers of adverse reactions are large. And the lack of regulation of compounded products might cause warnings about adverse reactions to fall through the cracks. In addition, even if they gave warnings about each individual ingredient in the compounded medicine, drugs sometimes have reactions when used in combination that are unpredictable or unforeseen. Below is a quote from an article about compounded medications and product liability
https://www.ncbi.nlm.nih.gov/pubmed/25276868 (portions highlighted for emphasis):
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Risk and liabilities of prescribing compounded medications.
Complications resulting from the use of compounded medications have become a troubling trend nationwide. There is a significant potential for patients to suffer serious harm from the use of substandard medications prepared by compounding pharmacies, and the reality of this problem has been demonstrated in several well-publicized incidences of serious medical complications, including patient deaths, that directly resulted from the use of medications prepared at compounding pharmacies. Unlike US Food and Drug Administration (FDA)-approved drugs, compounded products are not required to meet evidentiary standards for establishing safety and efficacy. Moreover, these products are not held to Good Manufacturing Practices, which require regular inspections, quality control testing, and rejection of material not meeting specifications. Physicians, as well as other prescribers, need to be aware that when a patient suffers harm from using a compounded medication, those injured patients may bring negligence and malpractice claims, not only against the pharmacy and the pharmacist responsible for preparing the medication, but also against the prescribing physician and the physician’s practice. Consequently, the best way for physicians to manage professional risk and avoid both litigation and potential negative patient outcomes related to compounded pharmaceuticals is to not use these products if there is an FDA-approved product available. However, if the use of a compounded medication is medically necessary, then physicians should adhere to the FDA guidance concerning traditional compounding. Moreover, it would be prudent for any physician who intends to either resell or participate in the distribution of compounded products beyond the direct treatment of their patients to consider obtaining the appropriate insurance coverage for this activity.
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My mission for today will be to collect articles on ototoxicity (the study of medicines that cause toxic reactions to the ears and hearing) and see if I can find out anything more about the possible side effects of these drugs. If I find anything else, I'll post it below.