Take a pic and post it here if you can.
To me, this sounds like a localized pyoderma infection (aka staph intermedius, aka a "hot spot"). This infection could easily go systemic, btw.
Does he have allergies or something? Does he chew/lick his paws?
For localized pyoderma, the treatment is usually Muciprocin ointment, which is prescription. If systemic, then it's Simplicef x 30 days. You could try putting antibiotic ointment on it 2x per day and see if that helps since it's still early.
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