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Originally Posted by pstinard  I checked out the DFA's references on menadione toxicity, and most of them involved large amounts of menadione (about 1 mM solution, which is quite a lot from a biological standpoint) that would never be purposefully fed to a dog. I think they were concerned about human exposure in labs that work with large quantities of menadione as a chemical reagent? One of the more interesting studies involved the injection of a human subject with menadione to counteract rat poisoning. He developed eczema at the injection site. Again, not likely to happen with dog food.
I found the following from the Handbook of Preservatives, by Michael and Irene Ash (2004): |
That said, if given a choice, I would choose a dog food that doesn't contain an unnecessary ingredient, especially if it's toxic in large quantities. I'm sure that dog foods containing menadione are generally harmless, but what if there is poor quality control and a larger amount slips in? Something to consider...