Introduction
In many parts of the world, due to cultural or economic prohibitions, bitches and dogs are not spayed or castrated unless they have reproductive tract disease. However, in the United States, virtually all bitches and dogs are rendered sterile by surgery at some point in their life. This better allows for reproduction control in animals no longer capable of or not considered desirable for breeding, and eliminates behaviors and physical changes related to presence of reproductive hormones that dog owners find objectionable. The surgeries most commonly performed are ovariohysterectomy (removal of the uterus and both ovaries), commonly called spaying, and castration (removal of both testes and the associated epididymes). Castration is commonly also called neutering, although that term most correctly can be used for surgery of either gender. Collectively, these surgeries can be referred to as gonadectomy, removal of the gonads or reproductive organs.
Removal of the ovaries eliminates secretion of the hormones estrogen and progesterone. Removal of the testes eliminates secretion of the hormone testosterone. Elimination of these hormones obviously leads to decreases in behaviors and physical changes associated with their secretion, such as heat behavior, swelling of the vulva, and estrous bleeding in bitches, and mounting and roaming in dogs. However, reproductive hormones have effects on other tissues in the body and removal of those hormones may inadvertently impact those systems negatively. Other, less obvious, hormone changes also occur after gonadectomy, including persistent elevation in hormones that control the secretion of estrogen, progesterone, and testosterone. Whether these other hormone changes affect other systems positively or negatively often is unclear.
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his paper is a review of what has been demonstrated in the veterinary literature regarding effect of gonadectomy on the animal as a whole. This discussion does not address the societal problem of pet overpopulation. The author feels that animals with no owner or guardian should be spayed or castrated before adoption into a new home as one of many initiatives necessary to decrease the number of dogs euthanized in the United States annually. This discussion instead refers to dogs with responsible owners or guardians who maintain dogs as household pets, do not allow the animals to roam free, and provide the animals with regular veterinary care.
Evidence in this context is defined as credible information from peer-reviewed research. Studies involving more dogs are more valuable than reports of single cases. Multiple studies documenting a given phenomenon are more valuable than single papers. Incidence in this context is reported as a percent; this is the number of affected animals out of a random sample of 100. In veterinary medicine, any condition with an incidence greater than 1% is considered common. Readers are encouraged to carefully read all manuscripts of interest and to ask their veterinarian for clarification if needed. This paper is condensed from a more detailed, extensively referenced manuscript that may be available through your veterinarian (Root Kustritz MV. Determining the optimal age for gonadectomy of dogs and cats. Journal of the American Veterinary Medical Association 2007;231(11):1665-1675).
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