I'm sure it will be fine. 

  Just take the proper precautions.  I wouldn't put her down in areas that are heavily populated by dogs - avoid dog parks, rest stops, etc, for putting her on the ground.  Many people travel w/ puppies, especially considering a lot of people will travel long distances to get a pup from a breeder, etc.  
As far as travel, I tend to over-pack w/ Jackson's things, knowing we are far away from home and can't just go back to the house if I forget something.  I bring multiple collars/leashes/tags in case one is lost or left somewhere or whatever. Always have tags on him with my cell # on it.  I bring food & treats of course.  I always have water bottles on me and a portable water bowl.  I bring some kind of ex-pen or gate for hotel rooms so I can block him away from the door- God forbid it gets opened and he gets loose or something. Bring any meds.. I like to bring Benadryl in case of a reaction of sorts, also I bring allergy meds in case he's having some kind of allergic reaction to environment. I bring toys & chews to keep him occupied when needed.  Umm I am probably missing some stuff. But that's the main.