Your thread title scared me. Glad it is not your boys, but sorry to hear this involves a relation.
From petMD, some causes of liver failure:
Quote:
Acute liver failure is most often caused by infectious agents or toxins, poor flow of fluids into the liver and surrounding tissues (perfusion), hypoxia (inability to breathe), drugs or chemicals that are destructive to the liver (hepatotoxic), and excess exposure to heat. Necrosis (tissue death) sets in, with loss of liver enzymes and impaired liver function ultimately leading to complete organ failure.
Acute liver failure also occurs due to extensive metabolic disorders in protein synthesis (albumin, transport protein, procoagulant and anticoagulant protein factors), and glucose absorption, as well as abnormalities in the metabolic detoxification process.
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Usually liver shunt would present symptoms, although not always, as Ladyjane found out with one of her pups. A shunt was discovered by accident while the dog was being treated for something else.