Yes I have used the Acepromazine and it helped. Bella is 7 pounds and I have used 1/4 of the pill and it made her a little sleepy but did not knock her out....you don't want that. I have also given her 1/2 of the tablet and it made her very droggy so I didn't do that again...she had nothing to eat that day and it hit her hard. My recommendation would be to try it on her at home to see how she reacts that way you will know. You don't want to give it to her the first time and get on a plane with not knowing how she will react to it.....If wears off quite quickly though |