I use frontline topspot on Mojo (cuz he is under 8 lbs) I only reaply every 40-50 days (it is suposed to last for almost 3 months on flea control) Mojo did get fleas once, and now i take care of the enviroment also, once a month i wash all the outside area with a flea and insect killer, i fogged the whole house and also once every 2 weeks use carpet powder with flea and insect killer...i just really hate fleas