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Ian had his teeth cleaned today, and had the sealant, Sanos applied. It is supposed to last for six months, but of course that depends if your dog uses "dental type toys," or hard toys. You are not supposed to brush their teeth with this sealant because it will gradually remove it. Ian's vet said that they can reapply it after six months, with a mild sedative. I read up on on it before deciding to use it...I felt that it was better than OralVet, and longer lasting. It's more expensive, but may save money in the log run.