From the Advantix II website:
For dogs in need of complete pest coverage, look to K9 Advantix II. K9 Advantix II helps repel and kill ticks, fleas and mosquitoes while preventing the development of all flea life stages. This full featured pest control formula contains imidacloprid, permethrin, and pyriproxyfen. Imidacloprid and permethrin paralyze and kill pests by attacking the nerve cells of the parasites. Pyriproxyfen is an insect growth regulator that helps stop fleas from developing into advanced stages of life.
From the Sentinel website:
Description:SENTINEL Flavor Tabs are available in four tablet sizes in color-coded packages for oral administration to dogs and puppies according to their weight. (See Dosage Section.) Each tablet is formulated to provide a minimum of 0.23 mg/lb (0.5 mg/kg) of milbemycin oxime and 4.55 mg/lb (10 mg/kg) body weight of lufenuron.
Milbemycin oxime consists of the oxime derivatives of 5-didehydromilbemycins in the ratio of approximately 80% A4 (C32H45NO7, MW 555.71) and 20% A3 (C31H43NO7, MW 541.68). Milbemycin oxime is classified as a macrocyclic anthelmintic.
Lufenuron is a benzoylphenylurea derivative with the following chemical composition: N-[2,5-dichloro- 4-(1,1,2,3,3,3,-hexafluoropropoxy)- phenylaminocarbonyl]-2,6 - difluorobenzamide (C17 H8 CI2F8N2O3 ,MW511.15). Benzoylphenylurea compounds, including lufenuron, are classified as insect development inhibitors (IDIs).
-----------------------------------
It looks like Advantix II has flea killers and flea growth inhibitors, whereas Sentinel has dewormer and flea growth inhibitors. I'm not sure how toxic the growth inhibitors are in combination--best to check with a vet first. |