Cairo, an Italian mastiff puppy, was introduced as a playmate to 10-week-old Koza, a lion cub whose twin died, at the San Diego Wild Animal Park. The idea is that lions are social animals, but there are no other lion cubs at the park for Koza to interact with. Cairo is the next best thing.
More pictures at link below...
http://photos.signonsandiego.com/gallery1.5/oddcouple