I have been using Trifexis for 11 doses in 2 dogs without any problems, but it can cause vomiting if you don't give it on a full stomach. I am very careful to do it immediately after their breakfast, so I haven't had a problem.
That being said:
1. Just because my dogs don't have a reaction, doesn't mean yours won't. It sounds like yours may have an issue that goes beyond digestive tolerance.
2. Even though I've been using it without incidence, I'm still not comfortable with it. I only started using it because Sentinel wasn't available.
3. When my pups go in for their annual next month, I'm considering going to Heartguard/Iverheart and not treating for fleas. I've never seen a flea on them, I think I can go a few months without flea treatment until Sentinel becomes available again.
Re Sentinel and Interceptor: Novartis are currently making trial runs to iron out the kinks in their production process / quality control and are expected to be able to start supplying vets in three or four months from now. Not that we can count on that exact time frame, but they are slowly making progress.
__________________ Life is merrier with a Yorkshire Terrier! Jezebel  & Chuy  ... RIP: Barkley  Loosie  & Sassy  |