You all have mentioned so many of mine already.
The worst offenders:
Stupidity
People who can obviously go to the bank, grocery store etc. At other times then Saturday afternoon or after people have gotten out of work. I don't have time be behind someone who is just their becuase they have nothing better to do.
People who are walking in front of you then just stop short and stand there. Move to the side.
People who have to beat you at the traffic light only to go 2 miles an hour.
Stupidity
Anything not picked up, made, put in its place or cleaned up. (No I really am not anal

)
People who don't proof reports and submit them anyway.
Did I say stupidity
People who constantly crictize others without looking at themselves.